Danchik C - Search Results

1

Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors.

Thakur A, Tawa GJ, Henderson MJ, Danchik C, Liu S, Shah P, Wang AQ, Dunn G, Kabir M, Padilha EC, Xu X, Simeonov A, Kharbanda S, Stone R, Grewal G. Thakur A, et al. Among authors: danchik c. J Med Chem. 2020 Apr 23;63(8):4256-4292. doi: 10.1021/acs.jmedchem.0c00193. Epub 2020 Apr 8. J Med Chem. 2020. PMID: 32212730 Free PMC article.

2

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.

Yang SM, Martinez NJ, Yasgar A, Danchik C, Johansson C, Wang Y, Baljinnyam B, Wang AQ, Xu X, Shah P, Cheff D, Wang XS, Roth J, Lal-Nag M, Dunford JE, Oppermann U, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ. Yang SM, et al. Among authors: danchik c. J Med Chem. 2018 Jun 14;61(11):4883-4903. doi: 10.1021/acs.jmedchem.8b00270. Epub 2018 May 31. J Med Chem. 2018. PMID: 29767973 Free PMC article.

3

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.

Yasgar A, Titus SA, Wang Y, Danchik C, Yang SM, Vasiliou V, Jadhav A, Maloney DJ, Simeonov A, Martinez NJ. Yasgar A, et al. Among authors: danchik c. PLoS One. 2017 Jan 27;12(1):e0170937. doi: 10.1371/journal.pone.0170937. eCollection 2017. PLoS One. 2017. PMID: 28129349 Free PMC article.

4

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.

Henderson MJ, Trychta KA, Yang SM, Bäck S, Yasgar A, Wires ES, Danchik C, Yan X, Yano H, Shi L, Wu KJ, Wang AQ, Tao D, Zahoránszky-Kőhalmi G, Hu X, Xu X, Maloney D, Zakharov AV, Rai G, Urano F, Airavaara M, Gavrilova O, Jadhav A, Wang Y, Simeonov A, Harvey BK. Henderson MJ, et al. Among authors: danchik c. Cell Rep. 2021 Apr 27;35(4):109040. doi: 10.1016/j.celrep.2021.109040. Cell Rep. 2021. PMID: 33910017 Free PMC article.

5

Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein-Protein Interactions with a Native VapB1 Inhibitor.

Sun H, Coussens NP, Danchik C, Wachsmuth LM, Henderson MJ, Patnaik S, Hall MD, Molinaro AL, Daines DA, Shen M. Sun H, et al. Among authors: danchik c. J Chem Inf Model. 2022 Mar 14;62(5):1249-1258. doi: 10.1021/acs.jcim.1c01188. Epub 2022 Feb 1. J Chem Inf Model. 2022. PMID: 35103473 Free PMC article.

6

A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.

Asawa RR, Danchik C, Zakharov A, Chen Y, Voss T, Jadhav A, Wallace DP, Trott JF, Weiss RH, Simeonov A, Martinez NJ. Asawa RR, et al. Among authors: danchik c. Sci Rep. 2020 Mar 6;10(1):4203. doi: 10.1038/s41598-020-61082-3. Sci Rep. 2020. PMID: 32144367 Free PMC article.

7

Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences.

Roth JS, Lee TD, Cheff DM, Gosztyla ML, Asawa RR, Danchik C, Michael S, Simeonov A, Klumpp-Thomas C, Wilson KM, Hall MD. Roth JS, et al. Among authors: danchik c. SLAS Discov. 2020 Jun;25(5):491-497. doi: 10.1177/2472555220911451. Epub 2020 Apr 1. SLAS Discov. 2020. PMID: 32233736 Free PMC article.

8

Author Correction: A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.

Asawa RR, Danchik C, Zakharov A, Chen Y, Voss T, Jadhav A, Wallace DP, Trott JF, Weiss RH, Simeonov A, Martinez NJ. Asawa RR, et al. Among authors: danchik c. Sci Rep. 2022 Oct 13;12(1):17185. doi: 10.1038/s41598-022-21947-1. Sci Rep. 2022. PMID: 36229506 Free PMC article. No abstract available.

9

Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.

Yasgar A, Titus SA, Wang Y, Danchik C, Yang SM, Vasiliou V, Jadhav A, Maloney DJ, Simeonov A, Martinez NJ. Yasgar A, et al. Among authors: danchik c. PLoS One. 2018 May 15;13(5):e0197292. doi: 10.1371/journal.pone.0197292. eCollection 2018. PLoS One. 2018. PMID: 29763427 Free PMC article.

10

Targeting the Mycobacterium tuberculosis Stringent Response as a Strategy for Shortening Tuberculosis Treatment.

Danchik C, Wang S, Karakousis PC. Danchik C, et al. Front Microbiol. 2021 Oct 7;12:744167. doi: 10.3389/fmicb.2021.744167. eCollection 2021. Front Microbiol. 2021. PMID: 34690990 Free PMC article. Review.

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