Gutkind JS - Search Results

1

Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis.

Goto Y, Ando T, Izumi H, Feng X, Arang N, Gilardi M, Wang Z, Ando K, Gutkind JS. Goto Y, et al. Among authors: gutkind js. Oncogene. 2020 May;39(20):4014-4027. doi: 10.1038/s41388-020-1272-x. Epub 2020 Mar 23. Oncogene. 2020. PMID: 32205868 Free PMC article.

2

Burstein ES, Hesterberg DJ, Gutkind JS, Brann MR, Currier EA, Messier TL. Burstein ES, et al. Among authors: gutkind js. Oncogene. 1998 Sep 24;17(12):1617-23. doi: 10.1038/sj.onc.1202067. Oncogene. 1998. PMID: 9794239

3

Accumulation of dephosphorylated 4EBP after mTOR inhibition with rapamycin is sufficient to disrupt paracrine transformation by the KSHV vGPCR oncogene.

Martin D, Nguyen Q, Molinolo A, Gutkind JS. Martin D, et al. Among authors: gutkind js. Oncogene. 2014 May 1;33(18):2405-12. doi: 10.1038/onc.2013.193. Epub 2013 May 27. Oncogene. 2014. PMID: 23708663

4

Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.

Feng X, Degese MS, Iglesias-Bartolome R, Vaque JP, Molinolo AA, Rodrigues M, Zaidi MR, Ksander BR, Merlino G, Sodhi A, Chen Q, Gutkind JS. Feng X, et al. Among authors: gutkind js. Cancer Cell. 2014 Jun 16;25(6):831-45. doi: 10.1016/j.ccr.2014.04.016. Epub 2014 May 29. Cancer Cell. 2014. PMID: 24882515 Free PMC article.

5

mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations.

Wang Z, Martin D, Molinolo AA, Patel V, Iglesias-Bartolome R, Degese MS, Vitale-Cross L, Chen Q, Gutkind JS. Wang Z, et al. Among authors: gutkind js. J Natl Cancer Inst. 2014 Aug 5;106(9):dju215. doi: 10.1093/jnci/dju215. Print 2014 Sep. J Natl Cancer Inst. 2014. PMID: 25099740 Free PMC article.

6

Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway.

Liu G, Yu FX, Kim YC, Meng Z, Naipauer J, Looney DJ, Liu X, Gutkind JS, Mesri EA, Guan KL. Liu G, et al. Among authors: gutkind js. Oncogene. 2015 Jul;34(27):3536-46. doi: 10.1038/onc.2014.281. Epub 2014 Sep 8. Oncogene. 2015. PMID: 25195862 Free PMC article.

7

Oncotargeting G proteins: The Hippo in the room.

Feng X, Chen Q, Gutkind JS. Feng X, et al. Among authors: gutkind js. Oncotarget. 2014 Nov 30;5(22):10997-9. doi: 10.18632/oncotarget.2815. Oncotarget. 2014. PMID: 25526026 Free PMC article.

8

Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.

Iglesias-Bartolome R, Torres D, Marone R, Feng X, Martin D, Simaan M, Chen M, Weinstein LS, Taylor SS, Molinolo AA, Gutkind JS. Iglesias-Bartolome R, et al. Among authors: gutkind js. Nat Cell Biol. 2015 Jun;17(6):793-803. doi: 10.1038/ncb3164. Epub 2015 May 11. Nat Cell Biol. 2015. PMID: 25961504 Free PMC article.

9

Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.

O'Hayre M, Inoue A, Kufareva I, Wang Z, Mikelis CM, Drummond RA, Avino S, Finkel K, Kalim KW, DiPasquale G, Guo F, Aoki J, Zheng Y, Lionakis MS, Molinolo AA, Gutkind JS. O'Hayre M, et al. Among authors: gutkind js. Oncogene. 2016 Jul 21;35(29):3771-80. doi: 10.1038/onc.2015.442. Epub 2015 Nov 30. Oncogene. 2016. PMID: 26616858 Free PMC article.

10

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers.

Yamaguchi K, Iglesias-Bartolomé R, Wang Z, Callejas-Valera JL, Amornphimoltham P, Molinolo AA, Cohen EE, Califano JA, Lippman SM, Luo J, Gutkind JS. Yamaguchi K, et al. Among authors: gutkind js. Oncotarget. 2016 Mar 8;7(10):10696-709. doi: 10.18632/oncotarget.7372. Oncotarget. 2016. PMID: 26882569 Free PMC article.

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