Wells JA - Search Results

1

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.

Leung KK, Wilson GM, Kirkemo LL, Riley NM, Coon JJ, Wells JA. Leung KK, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7764-7775. doi: 10.1073/pnas.1917947117. Epub 2020 Mar 23. Proc Natl Acad Sci U S A. 2020. PMID: 32205440 Free PMC article.

2

Two-state selection of conformation-specific antibodies.

Gao J, Sidhu SS, Wells JA. Gao J, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3071-6. doi: 10.1073/pnas.0812952106. Epub 2009 Feb 10. Proc Natl Acad Sci U S A. 2009. PMID: 19208804 Free PMC article.

3

Sampling the N-terminal proteome of human blood.

Wildes D, Wells JA. Wildes D, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4561-6. doi: 10.1073/pnas.0914495107. Epub 2010 Feb 19. Proc Natl Acad Sci U S A. 2010. PMID: 20173099 Free PMC article.

4

Turning a protein kinase on or off from a single allosteric site via disulfide trapping.

Sadowsky JD, Burlingame MA, Wolan DW, McClendon CL, Jacobson MP, Wells JA. Sadowsky JD, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6056-61. doi: 10.1073/pnas.1102376108. Epub 2011 Mar 23. Proc Natl Acad Sci U S A. 2011. PMID: 21430264 Free PMC article.

5

Global kinetic analysis of proteolysis via quantitative targeted proteomics.

Agard NJ, Mahrus S, Trinidad JC, Lynn A, Burlingame AL, Wells JA. Agard NJ, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1913-8. doi: 10.1073/pnas.1117158109. Epub 2012 Jan 23. Proc Natl Acad Sci U S A. 2012. PMID: 22308409 Free PMC article.

6

Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis.

Shimbo K, Hsu GW, Nguyen H, Mahrus S, Trinidad JC, Burlingame AL, Wells JA. Shimbo K, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12432-7. doi: 10.1073/pnas.1208616109. Epub 2012 Jul 16. Proc Natl Acad Sci U S A. 2012. PMID: 22802652 Free PMC article.

7

Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation.

Thomsen ND, Koerber JT, Wells JA. Thomsen ND, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8477-82. doi: 10.1073/pnas.1306759110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650375 Free PMC article.

8

Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling.

Wiita AP, Hsu GW, Lu CM, Esensten JH, Wells JA. Wiita AP, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7594-9. doi: 10.1073/pnas.1405987111. Epub 2014 May 12. Proc Natl Acad Sci U S A. 2014. PMID: 24821784 Free PMC article.

9

A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.

Rettenmaier TJ, Sadowsky JD, Thomsen ND, Chen SC, Doak AK, Arkin MR, Wells JA. Rettenmaier TJ, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18590-5. doi: 10.1073/pnas.1415365112. Epub 2014 Dec 17. Proc Natl Acad Sci U S A. 2014. PMID: 25518860 Free PMC article.

10

Engineered cellular gene-replacement platform for selective and inducible proteolytic profiling.

Morgan CW, Diaz JE, Zeitlin SG, Gray DC, Wells JA. Morgan CW, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8344-9. doi: 10.1073/pnas.1504141112. Epub 2015 Jun 23. Proc Natl Acad Sci U S A. 2015. PMID: 26106156 Free PMC article.

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