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Human Pluripotent Stem Cell-Derived Hepatocytes Show Higher Transcriptional Correlation with Adult Liver Tissue than with Fetal Liver Tissue.
Ghosheh N, Küppers-Munther B, Asplund A, Andersson CX, Björquist P, Andersson TB, Carén H, Simonsson S, Sartipy P, Synnergren J. Ghosheh N, et al. Among authors: andersson cx, andersson tb. ACS Omega. 2020 Mar 2;5(10):4816-4827. doi: 10.1021/acsomega.9b03514. eCollection 2020 Mar 17. ACS Omega. 2020. PMID: 32201767 Free PMC article.
Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project.
Mandenius CF, Andersson TB, Alves PM, Batzl-Hartmann C, Björquist P, Carrondo MJ, Chesne C, Coecke S, Edsbagge J, Fredriksson JM, Gerlach JC, Heinzle E, Ingelman-Sundberg M, Johansson I, Küppers-Munther B, Müller-Vieira U, Noor F, Zeilinger K. Mandenius CF, et al. Among authors: andersson tb. Altern Lab Anim. 2011 May;39(2):147-71. doi: 10.1177/026119291103900210. Altern Lab Anim. 2011. PMID: 21639679
Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.
Ulvestad M, Nordell P, Asplund A, Rehnström M, Jacobsson S, Holmgren G, Davidson L, Brolén G, Edsbagge J, Björquist P, Küppers-Munther B, Andersson TB. Ulvestad M, et al. Among authors: andersson tb. Biochem Pharmacol. 2013 Sep 1;86(5):691-702. doi: 10.1016/j.bcp.2013.06.029. Epub 2013 Jul 12. Biochem Pharmacol. 2013. PMID: 23856292
Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines.
Ghosheh N, Olsson B, Edsbagge J, Küppers-Munther B, Van Giezen M, Asplund A, Andersson TB, Björquist P, Carén H, Simonsson S, Sartipy P, Synnergren J. Ghosheh N, et al. Among authors: andersson tb. Stem Cells Int. 2016;2016:8648356. doi: 10.1155/2016/8648356. Epub 2016 Feb 1. Stem Cells Int. 2016. PMID: 26949401 Free PMC article.
Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.
Bell CC, Lauschke VM, Vorrink SU, Palmgren H, Duffin R, Andersson TB, Ingelman-Sundberg M. Bell CC, et al. Among authors: andersson tb. Drug Metab Dispos. 2017 Apr;45(4):419-429. doi: 10.1124/dmd.116.074369. Epub 2017 Jan 30. Drug Metab Dispos. 2017. PMID: 28137721 Free PMC article.
Comparative transcriptomics of hepatic differentiation of human pluripotent stem cells and adult human liver tissue.
Ghosheh N, Küppers-Munther B, Asplund A, Edsbagge J, Ulfenborg B, Andersson TB, Björquist P, Andersson CX, Carén H, Simonsson S, Sartipy P, Synnergren J. Ghosheh N, et al. Among authors: andersson cx, andersson tb. Physiol Genomics. 2017 Aug 1;49(8):430-446. doi: 10.1152/physiolgenomics.00007.2017. Epub 2017 Jul 10. Physiol Genomics. 2017. PMID: 28698227 Free article.
115 results