Zhou M - Search Results

1

HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2.

Yang X, Ji J, Liu C, Zhou M, Li H, Ye S, Hu Q. Yang X, et al. Among authors: zhou m. Int Immunopharmacol. 2020 Jun;83:106383. doi: 10.1016/j.intimp.2020.106383. Epub 2020 Mar 16. Int Immunopharmacol. 2020. PMID: 32193099

2

(E)-2-(4-bromophenyl)-1-(2, 4-dihydroxyphenyl)ethanone oxime is a potential therapeutic agent for treatment of hyperuricemia through its dual inhibitory effects on XOD and URAT1.

Hu Q, Zhou M, Zhu H, Lu G, Zheng D, Li H, Hao K. Hu Q, et al. Among authors: zhou m. Biomed Pharmacother. 2017 Feb;86:88-94. doi: 10.1016/j.biopha.2016.12.002. Epub 2016 Dec 9. Biomed Pharmacother. 2017. PMID: 27951420

3

Discovery of novel curcumin derivatives targeting xanthine oxidase and urate transporter 1 as anti-hyperuricemic agents.

Ao GZ, Zhou MZ, Li YY, Li SN, Wang HN, Wan QW, Li HQ, Hu QH. Ao GZ, et al. Bioorg Med Chem. 2017 Jan 1;25(1):166-174. doi: 10.1016/j.bmc.2016.10.022. Epub 2016 Oct 20. Bioorg Med Chem. 2017. PMID: 28340987

4

Emodinol ameliorates urate nephropathy by regulating renal organic ion transporters and inhibiting immune inflammatory responses in rats.

Wu H, Zhou M, Lu G, Yang Z, Ji H, Hu Q. Wu H, et al. Among authors: zhou m. Biomed Pharmacother. 2017 Dec;96:727-735. doi: 10.1016/j.biopha.2017.10.051. Epub 2017 Nov 6. Biomed Pharmacother. 2017. PMID: 29045935

5

Development of benzoxazole deoxybenzoin oxime and acyloxylamine derivatives targeting innate immune sensors and xanthine oxidase for treatment of gout.

Huang J, Zhou Z, Zhou M, Miao M, Li H, Hu Q. Huang J, et al. Among authors: zhou z, zhou m. Bioorg Med Chem. 2018 May 1;26(8):1653-1664. doi: 10.1016/j.bmc.2018.02.013. Epub 2018 Feb 12. Bioorg Med Chem. 2018. PMID: 29472126

6

4-(2-(4-chlorophenyl)-1-((4-chlorophenyl)amino)ethyl)benzene-1, 3-diol is a potential agent for gout therapy as a dual inhibitor of XOD and NLRP3.

Zhou M, Li S, Song L, Hu Q, Liu W. Zhou M, et al. Phytomedicine. 2018 Mar 15;42:9-17. doi: 10.1016/j.phymed.2018.03.007. Epub 2018 Mar 6. Phytomedicine. 2018. PMID: 29655702

7

Design, synthesis and anti-inflammatory evaluation of 3-amide benzoic acid derivatives as novel P2Y₁₄ receptor antagonists.

Zhang Z, Hao K, Li H, Lu R, Liu C, Zhou M, Li B, Meng Z, Hu Q, Jiang C. Zhang Z, et al. Among authors: zhou m. Eur J Med Chem. 2019 Nov 1;181:111564. doi: 10.1016/j.ejmech.2019.111564. Epub 2019 Jul 26. Eur J Med Chem. 2019. PMID: 31376563

8

Development of novel NLRP3-XOD dual inhibitors for the treatment of gout.

Wang W, Pang J, Ha EH, Zhou M, Li Z, Tian S, Li H, Hu Q. Wang W, et al. Among authors: zhou m. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126944. doi: 10.1016/j.bmcl.2019.126944. Epub 2020 Jan 2. Bioorg Med Chem Lett. 2020. PMID: 31924495

9

The role of P2Y₆R in cardiovascular diseases and recent development of P2Y₆R antagonists.

Zhou M, Wang W, Li Y, Zhang Q, Ji H, Li H, Hu Q. Zhou M, et al. Drug Discov Today. 2020 Mar;25(3):568-573. doi: 10.1016/j.drudis.2019.12.015. Epub 2020 Jan 8. Drug Discov Today. 2020. PMID: 31926135 Review.

10

P2Y₁₄ receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages.

Li H, Jiang W, Ye S, Zhou M, Liu C, Yang X, Hao K, Hu Q. Li H, et al. Among authors: zhou m. Cell Death Dis. 2020 May 26;11(5):394. doi: 10.1038/s41419-020-2609-7. Cell Death Dis. 2020. PMID: 32457291 Free PMC article.

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