Li H - Search Results

1

HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2.

Yang X, Ji J, Liu C, Zhou M, Li H, Ye S, Hu Q. Yang X, et al. Among authors: li h. Int Immunopharmacol. 2020 Jun;83:106383. doi: 10.1016/j.intimp.2020.106383. Epub 2020 Mar 16. Int Immunopharmacol. 2020. PMID: 32193099

2

Discovery of novel 4-anilinoquinazoline derivatives as potent inhibitors of epidermal growth factor receptor with antitumor activity.

Xu YY, Li SN, Yu GJ, Hu QH, Li HQ. Xu YY, et al. Bioorg Med Chem. 2013 Oct 1;21(19):6084-91. doi: 10.1016/j.bmc.2013.06.070. Epub 2013 Jul 10. Bioorg Med Chem. 2013. PMID: 23962660

3

Sodium tanshinone IIA sulfonate ameliorates ischemia-induced myocardial inflammation and lipid accumulation in Beagle dogs through NLRP3 inflammasome.

Hu Q, Wei B, Wei L, Hua K, Yu X, Li H, Ji H. Hu Q, et al. Among authors: li h. Int J Cardiol. 2015 Oct 1;196:183-92. doi: 10.1016/j.ijcard.2015.05.152. Epub 2015 May 29. Int J Cardiol. 2015. PMID: 26143630

4

(E)-2-(4-bromophenyl)-1-(2, 4-dihydroxyphenyl)ethanone oxime is a potential therapeutic agent for treatment of hyperuricemia through its dual inhibitory effects on XOD and URAT1.

Hu Q, Zhou M, Zhu H, Lu G, Zheng D, Li H, Hao K. Hu Q, et al. Among authors: li h. Biomed Pharmacother. 2017 Feb;86:88-94. doi: 10.1016/j.biopha.2016.12.002. Epub 2016 Dec 9. Biomed Pharmacother. 2017. PMID: 27951420

5

Discovery of novel curcumin derivatives targeting xanthine oxidase and urate transporter 1 as anti-hyperuricemic agents.

Ao GZ, Zhou MZ, Li YY, Li SN, Wang HN, Wan QW, Li HQ, Hu QH. Ao GZ, et al. Bioorg Med Chem. 2017 Jan 1;25(1):166-174. doi: 10.1016/j.bmc.2016.10.022. Epub 2016 Oct 20. Bioorg Med Chem. 2017. PMID: 28340987

6

Development of benzoxazole deoxybenzoin oxime and acyloxylamine derivatives targeting innate immune sensors and xanthine oxidase for treatment of gout.

Huang J, Zhou Z, Zhou M, Miao M, Li H, Hu Q. Huang J, et al. Among authors: li h. Bioorg Med Chem. 2018 May 1;26(8):1653-1664. doi: 10.1016/j.bmc.2018.02.013. Epub 2018 Feb 12. Bioorg Med Chem. 2018. PMID: 29472126

7

Development of novel NLRP3-XOD dual inhibitors for the treatment of gout.

Wang W, Pang J, Ha EH, Zhou M, Li Z, Tian S, Li H, Hu Q. Wang W, et al. Among authors: li z, li h. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126944. doi: 10.1016/j.bmcl.2019.126944. Epub 2020 Jan 2. Bioorg Med Chem Lett. 2020. PMID: 31924495

8

The role of P2Y₆R in cardiovascular diseases and recent development of P2Y₆R antagonists.

Zhou M, Wang W, Li Y, Zhang Q, Ji H, Li H, Hu Q. Zhou M, et al. Among authors: li y, li h. Drug Discov Today. 2020 Mar;25(3):568-573. doi: 10.1016/j.drudis.2019.12.015. Epub 2020 Jan 8. Drug Discov Today. 2020. PMID: 31926135 Review.

9

Discovery of novel and potent P2Y₁₄R antagonists via structure-based virtual screening for the treatment of acute gouty arthritis.

Wang W, Liu C, Li H, Tian S, Liu Y, Wang N, Yan D, Li H, Hu Q. Wang W, et al. Among authors: li h. J Adv Res. 2020 Feb 13;23:133-142. doi: 10.1016/j.jare.2020.02.007. eCollection 2020 May. J Adv Res. 2020. PMID: 32123586 Free PMC article.

10

Discovery and computational studies of 2-phenyl-benzoxazole acetamide derivatives as promising P2Y₁₄R antagonists with anti-gout potential.

Zhou M, Wang W, Wang Z, Wang Y, Zhu Y, Lin Z, Tian S, Huang Y, Hu Q, Li H. Zhou M, et al. Among authors: li h. Eur J Med Chem. 2022 Jan 5;227:113933. doi: 10.1016/j.ejmech.2021.113933. Epub 2021 Oct 19. Eur J Med Chem. 2022. PMID: 34689072

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