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522 results

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Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression.
Lin JD, Nishi H, Poles J, Niu X, Mccauley C, Rahman K, Brown EJ, Yeung ST, Vozhilla N, Weinstock A, Ramsey SA, Fisher EA, Loke P. Lin JD, et al. Among authors: brown ej. JCI Insight. 2019 Feb 21;4(4):e124574. doi: 10.1172/jci.insight.124574. eCollection 2019 Feb 21. JCI Insight. 2019. PMID: 30830865 Free PMC article.
Single-Cell RNA Sequencing of Visceral Adipose Tissue Leukocytes Reveals that Caloric Restriction Following Obesity Promotes the Accumulation of a Distinct Macrophage Population with Features of Phagocytic Cells.
Weinstock A, Brown EJ, Garabedian ML, Pena S, Sharma M, Lafaille J, Moore KJ, Fisher EA. Weinstock A, et al. Among authors: brown ej. Immunometabolism. 2019;1:e190008. doi: 10.20900/immunometab20190008. Epub 2019 Jul 19. Immunometabolism. 2019. PMID: 31396408 Free PMC article.
Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity.
Sharma M, Schlegel M, Brown EJ, Sansbury BE, Weinstock A, Afonso MS, Corr EM, van Solingen C, Shanley LC, Peled D, Ramasamy R, Schmidt AM, Spite M, Fisher EA, Moore KJ. Sharma M, et al. Among authors: brown ej. Immunometabolism. 2019;1(2):e190010. doi: 10.20900/immunometab20190010. Epub 2019 Aug 7. Immunometabolism. 2019. PMID: 31428465 Free PMC article.
Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression.
Sharma M, Schlegel MP, Afonso MS, Brown EJ, Rahman K, Weinstock A, Sansbury BE, Corr EM, van Solingen C, Koelwyn GJ, Shanley LC, Beckett L, Peled D, Lafaille JJ, Spite M, Loke P, Fisher EA, Moore KJ. Sharma M, et al. Among authors: brown ej. Circ Res. 2020 Jul 17;127(3):335-353. doi: 10.1161/CIRCRESAHA.119.316461. Epub 2020 Apr 27. Circ Res. 2020. PMID: 32336197 Free PMC article.
Myocardial infarction accelerates breast cancer via innate immune reprogramming.
Koelwyn GJ, Newman AAC, Afonso MS, van Solingen C, Corr EM, Brown EJ, Albers KB, Yamaguchi N, Narke D, Schlegel M, Sharma M, Shanley LC, Barrett TJ, Rahman K, Mezzano V, Fisher EA, Park DS, Newman JD, Quail DF, Nelson ER, Caan BJ, Jones LW, Moore KJ. Koelwyn GJ, et al. Among authors: brown ej. Nat Med. 2020 Sep;26(9):1452-1458. doi: 10.1038/s41591-020-0964-7. Epub 2020 Jul 13. Nat Med. 2020. PMID: 32661390 Free PMC article.
miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques.
Afonso MS, Sharma M, Schlegel M, van Solingen C, Koelwyn GJ, Shanley LC, Beckett L, Peled D, Rahman K, Giannarelli C, Li H, Brown EJ, Khodadadi-Jamayran A, Fisher EA, Moore KJ. Afonso MS, et al. Among authors: brown ej. Circ Res. 2021 Apr 16;128(8):1122-1138. doi: 10.1161/CIRCRESAHA.120.317914. Epub 2021 Feb 17. Circ Res. 2021. PMID: 33593073 Free PMC article.
Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis.
Weinstock A, Rahman K, Yaacov O, Nishi H, Menon P, Nikain CA, Garabedian ML, Pena S, Akbar N, Sansbury BE, Heffron SP, Liu J, Marecki G, Fernandez D, Brown EJ, Ruggles KV, Ramsey SA, Giannarelli C, Spite M, Choudhury RP, Loke P, Fisher EA. Weinstock A, et al. Among authors: brown ej. Elife. 2021 Mar 15;10:e67932. doi: 10.7554/eLife.67932. Elife. 2021. PMID: 33720008 Free PMC article.
Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice.
Voisin M, Shrestha E, Rollet C, Nikain CA, Josefs T, Mahé M, Barrett TJ, Chang HR, Ruoff R, Schneider JA, Garabedian ML, Zoumadakis C, Yun C, Badwan B, Brown EJ, Mar AC, Schneider RJ, Goldberg IJ, Pineda-Torra I, Fisher EA, Garabedian MJ. Voisin M, et al. Among authors: brown ej. Commun Biol. 2021 Mar 26;4(1):420. doi: 10.1038/s42003-021-01925-5. Commun Biol. 2021. PMID: 33772096 Free PMC article.
Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression.
Schlegel M, Sharma M, Brown EJ, Newman AAC, Cyr Y, Afonso MS, Corr EM, Koelwyn GJ, van Solingen C, Guzman J, Farhat R, Nikain CA, Shanley LC, Peled D, Schmidt AM, Fisher EA, Moore KJ. Schlegel M, et al. Among authors: brown ej. Circ Res. 2021 Aug 20;129(5):530-546. doi: 10.1161/CIRCRESAHA.121.319313. Epub 2021 Jul 22. Circ Res. 2021. PMID: 34289717 Free PMC article.
522 results