Iorio MT - Search Results

1

Erratum to "Defined concatenated α6α1β3γ2 GABAA receptor constructs reveal dual action of pyrazoloquinolinone allosteric modulators" [Bioorg. Med. Chem. 27 (2019) 3167-3178].

Simeone X, Iorio MT, Siebert DCB, Rehman S, Schnürch M, Mihovilovic MD, Ernst M. Simeone X, et al. Among authors: iorio mt. Bioorg Med Chem. 2020 Apr 15;28(8):115417. doi: 10.1016/j.bmc.2020.115417. Epub 2020 Mar 14. Bioorg Med Chem. 2020. PMID: 32184041 No abstract available.

2

Variations on a scaffold - Novel GABA_A receptor modulators.

Iorio MT, Rehman S, Bampali K, Stoeger B, Schnürch M, Ernst M, Mihovilovic MD. Iorio MT, et al. Eur J Med Chem. 2019 Oct 15;180:340-349. doi: 10.1016/j.ejmech.2019.07.008. Epub 2019 Jul 5. Eur J Med Chem. 2019. PMID: 31325782 Free article.

3

Defined concatenated α6α1β3γ2 GABA_A receptor constructs reveal dual action of pyrazoloquinolinone allosteric modulators.

Simeone X, Iorio MT, Siebert DCB, Rehman S, Schnürch M, Mihovilovic MD, Ernst M. Simeone X, et al. Among authors: iorio mt. Bioorg Med Chem. 2019 Jul 15;27(14):3167-3178. doi: 10.1016/j.bmc.2019.06.006. Epub 2019 Jun 5. Bioorg Med Chem. 2019. PMID: 31186146

4

GABA_A Receptor Ligands Often Interact with Binding Sites in the Transmembrane Domain and in the Extracellular Domain-Can the Promiscuity Code Be Cracked?

Iorio MT, Vogel FD, Koniuszewski F, Scholze P, Rehman S, Simeone X, Schnürch M, Mihovilovic MD, Ernst M. Iorio MT, et al. Int J Mol Sci. 2020 Jan 3;21(1):334. doi: 10.3390/ijms21010334. Int J Mol Sci. 2020. PMID: 31947863 Free PMC article.

5

Allosteric GABA_A Receptor Modulators-A Review on the Most Recent Heterocyclic Chemotypes and Their Synthetic Accessibility.

Vega Alanis BA, Iorio MT, Silva LL, Bampali K, Ernst M, Schnürch M, Mihovilovic MD. Vega Alanis BA, et al. Among authors: iorio mt. Molecules. 2020 Feb 24;25(4):999. doi: 10.3390/molecules25040999. Molecules. 2020. PMID: 32102309 Free PMC article. Review.

6

Synthesis and biological evaluation of triazolyl-substituted benzyloxyacetohydroxamic acids as LpxC inhibitors.

Hoff K, Mielniczuk S, Agoglitta O, Iorio MT, Caldara M, Bülbül EF, Melesina J, Sippl W, Holl R. Hoff K, et al. Among authors: iorio mt. Bioorg Med Chem. 2020 Jul 1;28(13):115529. doi: 10.1016/j.bmc.2020.115529. Epub 2020 Apr 25. Bioorg Med Chem. 2020. PMID: 32386952

7

Oncogenic ALK ^F1174L drives tumorigenesis in cutaneous squamous cell carcinoma.

Gualandi M, Iorio M, Engeler O, Serra-Roma A, Gasparre G, Schulte JH, Hohl D, Shakhova O. Gualandi M, et al. Life Sci Alliance. 2020 Apr 20;3(6):e201900601. doi: 10.26508/lsa.201900601. Print 2020 Jun. Life Sci Alliance. 2020. PMID: 32312912 Free PMC article.

8

The Neglected Liaison: Targeting Cancer Cell Metabolic Reprogramming Modifies the Composition of Non-Malignant Populations of the Tumor Microenvironment.

Iorio M, Umesh Ganesh N, De Luise M, Porcelli AM, Gasparre G, Kurelac I. Iorio M, et al. Cancers (Basel). 2021 Oct 29;13(21):5447. doi: 10.3390/cancers13215447. Cancers (Basel). 2021. PMID: 34771610 Free PMC article. Review.

9

Respiratory Complex I dysfunction in cancer: from a maze of cellular adaptive responses to potential therapeutic strategies.

Sollazzo M, De Luise M, Lemma S, Bressi L, Iorio M, Miglietta S, Milioni S, Kurelac I, Iommarini L, Gasparre G, Porcelli AM. Sollazzo M, et al. FEBS J. 2022 Dec;289(24):8003-8019. doi: 10.1111/febs.16218. Epub 2021 Oct 18. FEBS J. 2022. PMID: 34606156 Free PMC article. Review.

10

Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer.

De Luise M, Sollazzo M, Lama E, Coadă CA, Bressi L, Iorio M, Cavina B, D'Angelo L, Milioni S, Marchio L, Miglietta S, Coluccelli S, Tedesco G, Ghelli A, Lemma S, Perrone AM, Kurelac I, Iommarini L, Porcelli AM, Gasparre G. De Luise M, et al. Sci Rep. 2022 May 16;12(1):8020. doi: 10.1038/s41598-022-11620-y. Sci Rep. 2022. PMID: 35577908 Free PMC article.

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