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Page 1
Influence of disulfide bonds in human beta defensin-3 on its strain specific activity against Gram-negative bacteria.
Nehls C, Böhling A, Podschun R, Schubert S, Grötzinger J, Schromm A, Fedders H, Leippe M, Harder J, Kaconis Y, Gronow S, Gutsmann T. Nehls C, et al. Among authors: kaconis y. Biochim Biophys Acta Biomembr. 2020 Aug 1;1862(8):183273. doi: 10.1016/j.bbamem.2020.183273. Epub 2020 Mar 19. Biochim Biophys Acta Biomembr. 2020. PMID: 32171739 Free article.
Galleria mellonella native and analogue peptides Gm1 and ΔGm1. I) biophysical characterization of the interaction mechanisms with bacterial model membranes.
Correa W, Manrique-Moreno M, Patiño E, Peláez-Jaramillo C, Kaconis Y, Gutsmann T, Garidel P, Heinbockel L, Brandenburg K. Correa W, et al. Among authors: kaconis y. Biochim Biophys Acta. 2014 Oct;1838(10):2728-38. doi: 10.1016/j.bbamem.2014.07.006. Epub 2014 Jul 10. Biochim Biophys Acta. 2014. PMID: 25017800 Free article.
Cathelicidin and PMB neutralize endotoxins by multifactorial mechanisms including LPS interaction and targeting of host cell membranes.
Schromm AB, Paulowski L, Kaconis Y, Kopp F, Koistinen M, Donoghue A, Keese S, Nehls C, Wernecke J, Garidel P, Sevcsik E, Lohner K, Sanchez-Gomez S, Martinez-de-Tejada G, Brandenburg K, Brameshuber M, Schütz GJ, Andrä J, Gutsmann T. Schromm AB, et al. Among authors: kaconis y. Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2101721118. doi: 10.1073/pnas.2101721118. Proc Natl Acad Sci U S A. 2021. PMID: 34183393 Free PMC article.
Biophysical mechanisms of endotoxin neutralization by cationic amphiphilic peptides.
Kaconis Y, Kowalski I, Howe J, Brauser A, Richter W, Razquin-Olazarán I, Iñigo-Pestaña M, Garidel P, Rössle M, Martinez de Tejada G, Gutsmann T, Brandenburg K. Kaconis Y, et al. Biophys J. 2011 Jun 8;100(11):2652-61. doi: 10.1016/j.bpj.2011.04.041. Biophys J. 2011. PMID: 21641310 Free PMC article.
New antiseptic peptides to protect against endotoxin-mediated shock.
Gutsmann T, Razquin-Olazarán I, Kowalski I, Kaconis Y, Howe J, Bartels R, Hornef M, Schürholz T, Rössle M, Sanchez-Gómez S, Moriyon I, Martinez de Tejada G, Brandenburg K. Gutsmann T, et al. Among authors: kaconis y. Antimicrob Agents Chemother. 2010 Sep;54(9):3817-24. doi: 10.1128/AAC.00534-10. Epub 2010 Jul 6. Antimicrob Agents Chemother. 2010. PMID: 20606063 Free PMC article.
Preclinical investigations reveal the broad-spectrum neutralizing activity of peptide Pep19-2.5 on bacterial pathogenicity factors.
Heinbockel L, Sánchez-Gómez S, Martinez de Tejada G, Dömming S, Brandenburg J, Kaconis Y, Hornef M, Dupont A, Marwitz S, Goldmann T, Ernst M, Gutsmann T, Schürholz T, Brandenburg K. Heinbockel L, et al. Among authors: kaconis y. Antimicrob Agents Chemother. 2013 Mar;57(3):1480-7. doi: 10.1128/AAC.02066-12. Epub 2013 Jan 14. Antimicrob Agents Chemother. 2013. PMID: 23318793 Free PMC article.
Enhancing actions of peptides derived from the γ-chain of fetal human hemoglobin on the immunostimulant activities of monophosphoryl lipid A.
Ulmer AJ, Kaconis Y, Heinbockel L, Correa W, Alexander C, Rietschel ET, Mach JP, Gorczynski RM, Heini A, Rössle M, Richter W, Gutsmann T, Brandenburg K. Ulmer AJ, et al. Among authors: kaconis y. Innate Immun. 2016 Apr;22(3):168-80. doi: 10.1177/1753425916632304. Epub 2016 Feb 25. Innate Immun. 2016. PMID: 26921253 Free article.
16 results