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Small molecule therapeutics to treat the β-globinopathies.
Yu L, Myers G, Engel JD. Yu L, et al. Among authors: engel jd. Curr Opin Hematol. 2020 May;27(3):129-140. doi: 10.1097/MOH.0000000000000579. Curr Opin Hematol. 2020. PMID: 32167945 Free PMC article. Review.
Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes.
Campbell AD, Cui S, Shi L, Urbonya R, Mathias A, Bradley K, Bonsu KO, Douglas RR, Halford B, Schmidt L, Harro D, Giacherio D, Tanimoto K, Tanabe O, Engel JD. Campbell AD, et al. Among authors: engel jd. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18808-13. doi: 10.1073/pnas.1104964108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042865 Free PMC article.
Fetal Hemoglobin Induction by Epigenetic Drugs.
Lavelle D, Engel JD, Saunthararajah Y. Lavelle D, et al. Among authors: engel jd. Semin Hematol. 2018 Apr;55(2):60-67. doi: 10.1053/j.seminhematol.2018.04.008. Epub 2018 Apr 22. Semin Hematol. 2018. PMID: 29958562 Free PMC article. Review.
306 results