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Oral delivery of Hyperimmune bovine serum antibodies against CS6-expressing enterotoxigenic Escherichia coli as a prophylactic against diarrhea.
Talaat KR, Porter CK, Bourgeois AL, Lee TK, Duplessis CA, Maciel M Jr, Gutierrez RL, DeNearing B, Adjoodani B, Adkinson R, Testa KJ, Feijoo B, Alcala AN, Brubaker J, Beselman A, Chakraborty S, Sack D, Halpern J, Trop S, Wu H, Jiao J, Sullivan E, Riddle MS, Joseph SS, Poole ST, Prouty MG. Talaat KR, et al. Among authors: prouty mg. Gut Microbes. 2020 Nov 9;12(1):1732852. doi: 10.1080/19490976.2020.1732852. Epub 2020 Mar 13. Gut Microbes. 2020. PMID: 32167011 Free PMC article. Clinical Trial.
Enterotoxigenic E. coli virulence gene regulation in human infections.
Crofts AA, Giovanetti SM, Rubin EJ, Poly FM, Gutiérrez RL, Talaat KR, Porter CK, Riddle MS, DeNearing B, Brubaker J, Maciel M Jr, Alcala AN, Chakraborty S, Prouty MG, Savarino SJ, Davies BW, Trent MS. Crofts AA, et al. Among authors: prouty mg. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8968-E8976. doi: 10.1073/pnas.1808982115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30126994 Free PMC article. Clinical Trial.
Refinement of the CS6-expressing enterotoxigenic Escherichia coli strain B7A human challenge model: A randomized trial.
Talaat KR, Porter CK, Jaep KM, Duplessis CA, Gutierrez RL, Maciel M Jr, Adjoodani B, Feijoo B, Chakraborty S, Brubaker J, Trop SA, Riddle MS, Joseph SS, Bourgeois AL, Prouty MG. Talaat KR, et al. Among authors: prouty mg. PLoS One. 2020 Dec 2;15(12):e0239888. doi: 10.1371/journal.pone.0239888. eCollection 2020. PLoS One. 2020. PMID: 33264302 Free PMC article. Clinical Trial.
Safety and immunogenicity of intramuscularly administered CS6 subunit vaccine with a modified heat-labile enterotoxin from enterotoxigenic Escherichia coli.
Lee T, Gutiérrez RL, Maciel M, Poole S, Testa KJ, Trop S, Duplessis C, Lane A, Riddle MS, Hamer M, Alcala A, Prouty M, Maier N, Erdem R, Louis Bourgeois A, Porter CK. Lee T, et al. Vaccine. 2021 Sep 15;39(39):5548-5556. doi: 10.1016/j.vaccine.2021.08.032. Epub 2021 Aug 18. Vaccine. 2021. PMID: 34419306 Free PMC article. Clinical Trial.
Evaluation of the immunogenicity and protective efficacy of a recombinant CS6-based ETEC vaccine in an Aotus nancymaae CS6 + ETEC challenge model.
Ramakrishnan A, Joseph SS, Reynolds ND, Poncet D, Maciel M Jr, Nunez G, Espinoza N, Nieto M, Castillo R, Royal JM, Poole S, McVeigh A, Rollenhagen JE, Heinrichs J, Prouty MG, Simons MP, Renauld-Mongénie G, Savarino SJ. Ramakrishnan A, et al. Among authors: prouty mg. Vaccine. 2021 Jan 15;39(3):487-494. doi: 10.1016/j.vaccine.2020.12.034. Epub 2020 Dec 21. Vaccine. 2021. PMID: 33357957
Enterotoxigenic Escherichia coli-blood group A interactions intensify diarrheal severity.
Kumar P, Kuhlmann FM, Chakraborty S, Bourgeois AL, Foulke-Abel J, Tumala B, Vickers TJ, Sack DA, DeNearing B, Harro CD, Wright WS, Gildersleeve JC, Ciorba MA, Santhanam S, Porter CK, Gutierrez RL, Prouty MG, Riddle MS, Polino A, Sheikh A, Donowitz M, Fleckenstein JM. Kumar P, et al. Among authors: prouty mg. J Clin Invest. 2018 Aug 1;128(8):3298-3311. doi: 10.1172/JCI97659. Epub 2018 Jun 25. J Clin Invest. 2018. PMID: 29771685 Free PMC article. Clinical Trial.
Evaluation of the Immunogenicity and Protective Efficacy of an Enterotoxigenic Escherichia coli CFA/I Adhesin-Heat-Labile Toxin Chimera.
O'Dowd A, Maciel M Jr, Poole ST, Jobling MG, Rollenhagen JE, Woods CM, Sincock SA, McVeigh AL, Gregory MJ, Maves RC, Prouty MG, Holmes RK, Savarino SJ. O'Dowd A, et al. Among authors: prouty mg. Infect Immun. 2020 Oct 19;88(11):e00252-20. doi: 10.1128/IAI.00252-20. Print 2020 Oct 19. Infect Immun. 2020. PMID: 32839188 Free PMC article.
Developing and utilizing controlled human models of infection.
Porter CK, Louis Bourgeois A, Frenck RW, Prouty M, Maier N, Riddle MS. Porter CK, et al. Vaccine. 2017 Dec 14;35(49 Pt A):6813-6818. doi: 10.1016/j.vaccine.2017.05.068. Epub 2017 Jun 3. Vaccine. 2017. PMID: 28583306 Free article.
33 results