Wagg J - Search Results

1

Two distinct clinical patterns of checkpoint inhibitor-induced thyroid dysfunction.

Olsson-Brown A, Lord R, Sacco J, Wagg J, Coles M, Pirmohamed M. Olsson-Brown A, et al. Among authors: wagg j. Endocr Connect. 2020 Apr;9(4):318-325. doi: 10.1530/EC-19-0473. Endocr Connect. 2020. PMID: 32163916 Free PMC article.

2

An in silico model of cytotoxic T-lymphocyte activation in the lymph node following short peptide vaccination.

Brown LV, Gaffney EA, Wagg J, Coles MC. Brown LV, et al. Among authors: wagg j. J R Soc Interface. 2018 Mar;15(140):20180041. doi: 10.1098/rsif.2018.0041. J R Soc Interface. 2018. PMID: 29540543 Free PMC article.

3

Combining Mathematical Models With Experimentation to Drive Novel Mechanistic Insights Into Macrophage Function.

Jansen JE, Gaffney EA, Wagg J, Coles MC. Jansen JE, et al. Among authors: wagg j. Front Immunol. 2019 Jun 6;10:1283. doi: 10.3389/fimmu.2019.01283. eCollection 2019. Front Immunol. 2019. PMID: 31244837 Free PMC article.

4

Quantifying the limits of CAR T-cell delivery in mice and men.

Brown LV, Gaffney EA, Ager A, Wagg J, Coles MC. Brown LV, et al. Among authors: wagg j. J R Soc Interface. 2021 Mar;18(176):20201013. doi: 10.1098/rsif.2020.1013. Epub 2021 Mar 3. J R Soc Interface. 2021. PMID: 33653113 Free PMC article.

5

De-risking clinical trial failure through mechanistic simulation.

Brown LV, Wagg J, Darley R, van Hateren A, Elliott T, Gaffney EA, Coles MC. Brown LV, et al. Among authors: wagg j. Immunother Adv. 2022 Aug 23;2(1):ltac017. doi: 10.1093/immadv/ltac017. eCollection 2022. Immunother Adv. 2022. PMID: 36176591 Free PMC article.

6

Applications of mechanistic modelling to clinical and experimental immunology: an emerging technology to accelerate immunotherapeutic discovery and development.

Brown LV, Gaffney EA, Wagg J, Coles MC. Brown LV, et al. Among authors: wagg j. Clin Exp Immunol. 2018 Sep;193(3):284-292. doi: 10.1111/cei.13182. Clin Exp Immunol. 2018. PMID: 30240512 Free PMC article. Review.

7

Predicted limited redistribution of T cells to secondary lymphoid tissue correlates with increased risk of haematological malignancies in asplenic patients.

Kmieciak AE, Brown LV, Coles MC, Wagg J, Phipps A, Gaffney EA. Kmieciak AE, et al. Among authors: wagg j. Sci Rep. 2021 Aug 12;11(1):16394. doi: 10.1038/s41598-021-95225-x. Sci Rep. 2021. PMID: 34385480 Free PMC article.

8

Vascular phenotype identification and anti-angiogenic treatment recommendation: A pseudo-multiscale mathematical model of angiogenesis.

Hutchinson LG, Gaffney EA, Maini PK, Wagg J, Phipps A, Byrne HM. Hutchinson LG, et al. Among authors: wagg j. J Theor Biol. 2016 Jun 7;398:162-80. doi: 10.1016/j.jtbi.2016.03.002. Epub 2016 Mar 14. J Theor Biol. 2016. PMID: 26987523

9

Modeling Longitudinal Preclinical Tumor Size Data to Identify Transient Dynamics in Tumor Response to Antiangiogenic Drugs.

Hutchinson LG, Mueller HJ, Gaffney EA, Maini PK, Wagg J, Phipps A, Boetsch C, Byrne HM, Ribba B. Hutchinson LG, et al. Among authors: wagg j. CPT Pharmacometrics Syst Pharmacol. 2016 Nov;5(11):636-645. doi: 10.1002/psp4.12142. Epub 2016 Nov 14. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27863175 Free PMC article.

10

Models and Machines: How Deep Learning Will Take Clinical Pharmacology to the Next Level.

Hutchinson L, Steiert B, Soubret A, Wagg J, Phipps A, Peck R, Charoin JE, Ribba B. Hutchinson L, et al. Among authors: wagg j. CPT Pharmacometrics Syst Pharmacol. 2019 Mar;8(3):131-134. doi: 10.1002/psp4.12377. Epub 2019 Feb 3. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 30549240 Free PMC article.

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