Cai K - Search Results

1

ISCU interacts with NFU1, and ISCU[4Fe-4S] transfers its Fe-S cluster to NFU1 leading to the production of holo-NFU1.

Cai K, Frederick RO, Markley JL. Cai K, et al. J Struct Biol. 2020 May 1;210(2):107491. doi: 10.1016/j.jsb.2020.107491. Epub 2020 Mar 6. J Struct Biol. 2020. PMID: 32151725 Free PMC article.

2

Metamorphic protein IscU alternates conformations in the course of its role as the scaffold protein for iron-sulfur cluster biosynthesis and delivery.

Markley JL, Kim JH, Dai Z, Bothe JR, Cai K, Frederick RO, Tonelli M. Markley JL, et al. Among authors: cai k. FEBS Lett. 2013 Apr 17;587(8):1172-9. doi: 10.1016/j.febslet.2013.01.003. Epub 2013 Jan 16. FEBS Lett. 2013. PMID: 23333622 Free PMC article. Review.

3

Electron transfer mechanism of the Rieske protein from Thermus thermophilus from solution nuclear magnetic resonance investigations.

Hsueh KL, Tonelli M, Cai K, Westler WM, Markley JL. Hsueh KL, et al. Among authors: cai k. Biochemistry. 2013 Apr 30;52(17):2862-73. doi: 10.1021/bi400296c. Epub 2013 Apr 15. Biochemistry. 2013. PMID: 23480240 Free PMC article.

4

Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the iron-sulfur cluster scaffold protein (ISCU).

Cai K, Frederick RO, Kim JH, Reinen NM, Tonelli M, Markley JL. Cai K, et al. J Biol Chem. 2013 Oct 4;288(40):28755-70. doi: 10.1074/jbc.M113.482042. Epub 2013 Aug 12. J Biol Chem. 2013. PMID: 23940031 Free PMC article.

5

The specialized Hsp70 (HscA) interdomain linker binds to its nucleotide-binding domain and stimulates ATP hydrolysis in both cis and trans configurations.

Alderson TR, Kim JH, Cai K, Frederick RO, Tonelli M, Markley JL. Alderson TR, et al. Among authors: cai k. Biochemistry. 2014 Nov 25;53(46):7148-59. doi: 10.1021/bi5010552. Epub 2014 Nov 11. Biochemistry. 2014. PMID: 25372495 Free PMC article.

6

Structural/Functional Properties of Human NFU1, an Intermediate [4Fe-4S] Carrier in Human Mitochondrial Iron-Sulfur Cluster Biogenesis.

Cai K, Liu G, Frederick RO, Xiao R, Montelione GT, Markley JL. Cai K, et al. Structure. 2016 Dec 6;24(12):2080-2091. doi: 10.1016/j.str.2016.08.020. Epub 2016 Nov 3. Structure. 2016. PMID: 27818104 Free PMC article.

7

Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis.

Cai K, Tonelli M, Frederick RO, Markley JL. Cai K, et al. Biochemistry. 2017 Jan 24;56(3):487-499. doi: 10.1021/acs.biochem.6b00447. Epub 2017 Jan 11. Biochemistry. 2017. PMID: 28001042 Free PMC article.

8

Mitochondrial Cysteine Desulfurase and ISD11 Coexpressed in Escherichia coli Yield Complex Containing Acyl Carrier Protein.

Cai K, Frederick RO, Tonelli M, Markley JL. Cai K, et al. ACS Chem Biol. 2017 Apr 21;12(4):918-921. doi: 10.1021/acschembio.6b01005. Epub 2017 Mar 2. ACS Chem Biol. 2017. PMID: 28233492 Free PMC article.

9

ISCU(M108I) and ISCU(D39V) Differ from Wild-Type ISCU in Their Failure To Form Cysteine Desulfurase Complexes Containing Both Frataxin and Ferredoxin.

Cai K, Frederick RO, Tonelli M, Markley JL. Cai K, et al. Biochemistry. 2018 Mar 6;57(9):1491-1500. doi: 10.1021/acs.biochem.7b01234. Epub 2018 Feb 14. Biochemistry. 2018. PMID: 29406711 Free PMC article.

10

Interactions of iron-bound frataxin with ISCU and ferredoxin on the cysteine desulfurase complex leading to Fe-S cluster assembly.

Cai K, Frederick RO, Tonelli M, Markley JL. Cai K, et al. J Inorg Biochem. 2018 Jun;183:107-116. doi: 10.1016/j.jinorgbio.2018.03.007. Epub 2018 Mar 15. J Inorg Biochem. 2018. PMID: 29576242 Free PMC article.

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