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Decrease of core 2 O-glycans on synovial lubricin in osteoarthritis reduces galectin-3 mediated crosslinking.
Flowers SA, Thomsson KA, Ali L, Huang S, Mthembu Y, Regmi SC, Holgersson J, Schmidt TA, Rolfson O, Björkman LI, Sundqvist M, Karlsson-Bengtsson A, Jay GD, Eisler T, Krawetz R, Karlsson NG. Flowers SA, et al. Among authors: bjorkman li. J Biol Chem. 2020 Nov 20;295(47):16023-16036. doi: 10.1074/jbc.RA120.012882. Epub 2020 Sep 14. J Biol Chem. 2020. PMID: 32928962 Free PMC article.
Truncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1α: Interplay between O-linked glycosylation and inflammatory cytokines.
Huang S, Thomsson KA, Jin C, Ryberg H, Das N, Struglics A, Rolfson O, Björkman LI, Eisler T, Schmidt TA, Jay GD, Krawetz R, Karlsson NG. Huang S, et al. Among authors: bjorkman li. Front Mol Biosci. 2022 Sep 21;9:942406. doi: 10.3389/fmolb.2022.942406. eCollection 2022. Front Mol Biosci. 2022. PMID: 36213120 Free PMC article.
48 results