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Page 1
Engineered GPCRs as tools to modulate signal transduction.
Pei Y, Rogan SC, Yan F, Roth BL. Pei Y, et al. Among authors: roth bl. Physiology (Bethesda). 2008 Dec;23:313-21. doi: 10.1152/physiol.00025.2008. Physiology (Bethesda). 2008. PMID: 19074739 Free article. Review.
A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons.
Farrell MS, Pei Y, Wan Y, Yadav PN, Daigle TL, Urban DJ, Lee HM, Sciaky N, Simmons A, Nonneman RJ, Huang XP, Hufeisen SJ, Guettier JM, Moy SS, Wess J, Caron MG, Calakos N, Roth BL. Farrell MS, et al. Among authors: roth bl. Neuropsychopharmacology. 2013 Apr;38(5):854-62. doi: 10.1038/npp.2012.251. Epub 2012 Dec 5. Neuropsychopharmacology. 2013. PMID: 23303063 Free PMC article.
Conformational ensembles in GPCR activation.
Vardy E, Roth BL. Vardy E, et al. Among authors: roth bl. Cell. 2013 Jan 31;152(3):385-6. doi: 10.1016/j.cell.2013.01.025. Cell. 2013. PMID: 23374334 Free article.
DREADDs: novel tools for drug discovery and development.
Lee HM, Giguere PM, Roth BL. Lee HM, et al. Among authors: roth bl. Drug Discov Today. 2014 Apr;19(4):469-73. doi: 10.1016/j.drudis.2013.10.018. Epub 2013 Nov 1. Drug Discov Today. 2014. PMID: 24184433 Free PMC article. Review.
Allosteric sodium in class A GPCR signaling.
Katritch V, Fenalti G, Abola EE, Roth BL, Cherezov V, Stevens RC. Katritch V, et al. Among authors: roth bl. Trends Biochem Sci. 2014 May;39(5):233-44. doi: 10.1016/j.tibs.2014.03.002. Epub 2014 Apr 21. Trends Biochem Sci. 2014. PMID: 24767681 Free PMC article.
DREADD: a chemogenetic GPCR signaling platform.
Zhu H, Roth BL. Zhu H, et al. Among authors: roth bl. Int J Neuropsychopharmacol. 2014 Oct 31;18(1):pyu007. doi: 10.1093/ijnp/pyu007. Int J Neuropsychopharmacol. 2014. PMID: 25522378 Free PMC article.
547 results