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Page 1
The 'Digital Twin' to enable the vision of precision cardiology.
Corral-Acero J, Margara F, Marciniak M, Rodero C, Loncaric F, Feng Y, Gilbert A, Fernandes JF, Bukhari HA, Wajdan A, Martinez MV, Santos MS, Shamohammdi M, Luo H, Westphal P, Leeson P, DiAchille P, Gurev V, Mayr M, Geris L, Pathmanathan P, Morrison T, Cornelussen R, Prinzen F, Delhaas T, Doltra A, Sitges M, Vigmond EJ, Zacur E, Grau V, Rodriguez B, Remme EW, Niederer S, Mortier P, McLeod K, Potse M, Pueyo E, Bueno-Orovio A, Lamata P. Corral-Acero J, et al. Among authors: margara f. Eur Heart J. 2020 Dec 21;41(48):4556-4564. doi: 10.1093/eurheartj/ehaa159. Eur Heart J. 2020. PMID: 32128588 Free PMC article.
Sensitivity analysis of a strongly-coupled human-based electromechanical cardiac model: Effect of mechanical parameters on physiologically relevant biomarkers.
Levrero-Florencio F, Margara F, Zacur E, Bueno-Orovio A, Wang ZJ, Santiago A, Aguado-Sierra J, Houzeaux G, Grau V, Kay D, Vázquez M, Ruiz-Baier R, Rodriguez B. Levrero-Florencio F, et al. Among authors: margara f. Comput Methods Appl Mech Eng. 2020 Apr 1;361:112762. doi: 10.1016/j.cma.2019.112762. Comput Methods Appl Mech Eng. 2020. PMID: 32565583 Free PMC article.
CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.
Psaras Y, Margara F, Cicconet M, Sparrow AJ, Repetti GG, Schmid M, Steeples V, Wilcox JAL, Bueno-Orovio A, Redwood CS, Watkins HC, Robinson P, Rodriguez B, Seidman JG, Seidman CE, Toepfer CN. Psaras Y, et al. Among authors: margara f. Circ Res. 2021 Jul 9;129(2):326-341. doi: 10.1161/CIRCRESAHA.121.318868. Epub 2021 May 21. Circ Res. 2021. PMID: 34018815 Free PMC article.
Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM.
Pioner JM, Vitale G, Steczina S, Langione M, Margara F, Santini L, Giardini F, Lazzeri E, Piroddi N, Scellini B, Palandri C, Schuldt M, Spinelli V, Girolami F, Mazzarotto F, van der Velden J, Cerbai E, Tesi C, Olivotto I, Bueno-Orovio A, Sacconi L, Coppini R, Ferrantini C, Regnier M, Poggesi C. Pioner JM, et al. Among authors: margara f. Circ Res. 2023 Mar 3;132(5):628-644. doi: 10.1161/CIRCRESAHA.122.321956. Epub 2023 Feb 6. Circ Res. 2023. PMID: 36744470 Free PMC article.