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Page 1
Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy.
Ovadia C, Perdones-Montero A, Fan HM, Mullish BH, McDonald JAK, Papacleovoulou G, Wahlström A, Ståhlman M, Tsakmaki A, Clarke LCD, Sklavounos A, Dixon PH, Bewick GA, Walters JRF, Marschall HU, Marchesi JR, Williamson C. Ovadia C, et al. Among authors: papacleovoulou g. Sci Rep. 2020 Mar 3;10(1):3895. doi: 10.1038/s41598-020-60821-w. Sci Rep. 2020. PMID: 32127609 Free PMC article.
Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype.
Abu-Hayyeh S, Papacleovoulou G, Lövgren-Sandblom A, Tahir M, Oduwole O, Jamaludin NA, Ravat S, Nikolova V, Chambers J, Selden C, Rees M, Marschall HU, Parker MG, Williamson C. Abu-Hayyeh S, et al. Among authors: papacleovoulou g. Hepatology. 2013 Feb;57(2):716-26. doi: 10.1002/hep.26055. Epub 2013 Jan 8. Hepatology. 2013. PMID: 22961653 Free PMC article.
Maternal cholestasis during pregnancy programs metabolic disease in offspring.
Papacleovoulou G, Abu-Hayyeh S, Nikolopoulou E, Briz O, Owen BM, Nikolova V, Ovadia C, Huang X, Vaarasmaki M, Baumann M, Jansen E, Albrecht C, Jarvelin MR, Marin JJ, Knisely AS, Williamson C. Papacleovoulou G, et al. J Clin Invest. 2013 Jul;123(7):3172-81. doi: 10.1172/JCI68927. Epub 2013 Jun 24. J Clin Invest. 2013. PMID: 23934127 Free PMC article.
Gestational disruptions in metabolic rhythmicity of the liver, muscle, and placenta affect fetal size.
Papacleovoulou G, Nikolova V, Oduwole O, Chambers J, Vazquez-Lopez M, Jansen E, Nicolaides K, Parker M, Williamson C. Papacleovoulou G, et al. FASEB J. 2017 Apr;31(4):1698-1708. doi: 10.1096/fj.201601032R. Epub 2017 Jan 12. FASEB J. 2017. PMID: 28082353 Free PMC article.
In summary, disruptions in metabolic and circadian rhythmicity are associated with increased fetal size, with implications for the pathogenesis of macrosomia.-Papacleovoulou, G., Nikolova, V., Oduwole, O., Chambers, J., Vazquez-Lopez, M., Jansen, E., Nicolaides, K., …
In summary, disruptions in metabolic and circadian rhythmicity are associated with increased fetal size, with implications for the pathogene …
Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis.
Nikolova V, Papacleovoulou G, Bellafante E, Borges Manna L, Jansen E, Baron S, Abu-Hayyeh S, Parker M, Williamson C. Nikolova V, et al. Among authors: papacleovoulou g. Am J Physiol Endocrinol Metab. 2017 Oct 1;313(4):E463-E472. doi: 10.1152/ajpendo.00449.2016. Epub 2017 Apr 18. Am J Physiol Endocrinol Metab. 2017. PMID: 28420650 Free PMC article.
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