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Insertional activation of STAT3 and LCK by HIV-1 proviruses in T cell lymphomas.
Mellors JW, Guo S, Naqvi A, Brandt LD, Su L, Sun Z, Joseph KW, Demirov D, Halvas EK, Butcher D, Scott B, Hamilton A, Heil M, Karim B, Wu X, Hughes SH. Mellors JW, et al. Among authors: karim b. Sci Adv. 2021 Oct 15;7(42):eabi8795. doi: 10.1126/sciadv.abi8795. Epub 2021 Oct 13. Sci Adv. 2021. PMID: 34644108 Free PMC article.
Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial.
Abel ML, Takahashi N, Peer C, Redon CE, Nichols S, Vilimas R, Lee MJ, Lee S, Shelat M, Kattappuram R, Sciuto L, Pinkiert D, Graham C, Butcher D, Karim B, Sharma AK, Malin J, Kumar R, Schultz CW, Goyal S, Del Rivero J, Krishnamurthy M, Upadhyay D, Schroeder B, Sissung T, Tyagi M, Kim J, Pommier Y, Aladjem M, Raffeld M, Figg WD, Trepel J, Xi L, Desai P, Thomas A. Abel ML, et al. Among authors: karim b. Clin Cancer Res. 2023 Sep 15;29(18):3603-3611. doi: 10.1158/1078-0432.CCR-23-0536. Clin Cancer Res. 2023. PMID: 37227187 Free PMC article.
Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned.
Stransky LA, Gao W, Schmidt LS, Bi K, Ricketts CJ, Ramesh V, James A, Difilippantonio S, Ileva L, Kalen JD, Karim B, Jeon A, Morgan T, Warner AC, Turan S, Unite J, Tran B, Choudhari S, Zhao Y, Linn DE, Yun C, Dhandapani S, Parab V, Pinheiro EM, Morris N, He L, Vigeant SM, Pignon JC, Sticco-Ivins M, Signoretti S, Van Allen EM, Linehan WM, Kaelin WG Jr. Stransky LA, et al. Among authors: karim b. Proc Natl Acad Sci U S A. 2024 Oct 8;121(41):e2408549121. doi: 10.1073/pnas.2408549121. Epub 2024 Oct 4. Proc Natl Acad Sci U S A. 2024. PMID: 39365820 Free PMC article.
Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence.
Tomasetti C, Poling J, Roberts NJ, London NR Jr, Pittman ME, Haffner MC, Rizzo A, Baras A, Karim B, Kim A, Heaphy CM, Meeker AK, Hruban RH, Iacobuzio-Donahue CA, Vogelstein B. Tomasetti C, et al. Among authors: karim b. Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20482-20488. doi: 10.1073/pnas.1905722116. Epub 2019 Sep 23. Proc Natl Acad Sci U S A. 2019. PMID: 31548407 Free PMC article.
Surface-fill hydrogel attenuates the oncogenic signature of complex anatomical surface cancer in a single application.
Majumder P, Singh A, Wang Z, Dutta K, Pahwa R, Liang C, Andrews C, Patel NL, Shi J, de Val N, Walsh STR, Jeon AB, Karim B, Hoang CD, Schneider JP. Majumder P, et al. Among authors: karim b. Nat Nanotechnol. 2021 Nov;16(11):1251-1259. doi: 10.1038/s41565-021-00961-w. Epub 2021 Sep 23. Nat Nanotechnol. 2021. PMID: 34556833 Free PMC article.
138 results