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Pathogenic PTPN11 variants involving the poly-glutamine Gln255 -Gln256 -Gln257 stretch highlight the relevance of helix B in SHP2's functional regulation.
Martinelli S, Pannone L, Lissewski C, Brinkmann J, Flex E, Schanze D, Calligari P, Anselmi M, Pantaleoni F, Canale VC, Radio FC, Ioannides A, Rahner N, Schanze I, Josifova D, Bocchinfuso G, Ryten M, Stella L, Tartaglia M, Zenker M. Martinelli S, et al. Among authors: canale vc. Hum Mutat. 2020 Jun;41(6):1171-1182. doi: 10.1002/humu.24007. Epub 2020 Mar 11. Hum Mutat. 2020. PMID: 32112654
Targeting Oncogenic Src Homology 2 Domain-Containing Phosphatase 2 (SHP2) by Inhibiting Its Protein-Protein Interactions.
Bobone S, Pannone L, Biondi B, Solman M, Flex E, Canale VC, Calligari P, De Faveri C, Gandini T, Quercioli A, Torini G, Venditti M, Lauri A, Fasano G, Hoeksma J, Santucci V, Cattani G, Bocedi A, Carpentieri G, Tirelli V, Sanchez M, Peggion C, Formaggio F, den Hertog J, Martinelli S, Bocchinfuso G, Tartaglia M, Stella L. Bobone S, et al. Among authors: canale vc. J Med Chem. 2021 Nov 11;64(21):15973-15990. doi: 10.1021/acs.jmedchem.1c01371. Epub 2021 Oct 29. J Med Chem. 2021. PMID: 34714648 Free PMC article.
Binding of an antimicrobial peptide to bacterial cells: Interaction with different species, strains and cellular components.
Savini F, Loffredo MR, Troiano C, Bobone S, Malanovic N, Eichmann TO, Caprio L, Canale VC, Park Y, Mangoni ML, Stella L. Savini F, et al. Among authors: canale vc. Biochim Biophys Acta Biomembr. 2020 Aug 1;1862(8):183291. doi: 10.1016/j.bbamem.2020.183291. Epub 2020 Mar 28. Biochim Biophys Acta Biomembr. 2020. PMID: 32234322 Free article.
Botryoid rhabdomyosarcoma of the nasopharynx.
Canale VC, Volpe R, Carbone A, Grigoletto E. Canale VC, et al. J Laryngol Otol. 1983 Jun;97(6):553-6. doi: 10.1017/s0022215100094561. J Laryngol Otol. 1983. PMID: 6864097
22 results