Graham LJ - Search Results

1

The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer.

Luker AJ, Graham LJ, Smith TM Jr, Camarena C, Zellner MP, Gilmer JS, Damle SR, Conrad DH, Bear HD, Martin RK. Luker AJ, et al. Among authors: graham lj. BMC Immunol. 2020 Feb 27;21(1):8. doi: 10.1186/s12865-020-0337-5. BMC Immunol. 2020. PMID: 32106810 Free PMC article.

2

Protective role of IL-2 during activation of T cells with bryostatin 1.

Kos FJ, Cornell DL, Lipke AB, Graham LJ, Bear HD. Kos FJ, et al. Among authors: graham lj. Int J Immunopharmacol. 2000 Aug;22(8):645-52. doi: 10.1016/s0192-0561(00)00027-8. Int J Immunopharmacol. 2000. PMID: 10988359

3

Bryostatin/ionomycin-activated T cells mediate regression of established tumors.

Chin CS, Graham LJ, Hamad GG, George KR, Bear HD. Chin CS, et al. Among authors: graham lj. J Surg Res. 2001 Jun 15;98(2):108-15. doi: 10.1006/jsre.2001.6181. J Surg Res. 2001. PMID: 11397126

4

Successful adoptive immunotherapy with vaccine-sensitized T cells, despite no effect with vaccination alone in a weakly immunogenic tumor model.

Parviz M, Chin CS, Graham LJ, Miller C, Lee C, George K, Bear HD. Parviz M, et al. Among authors: graham lj. Cancer Immunol Immunother. 2003 Dec;52(12):739-50. doi: 10.1007/s00262-003-0405-8. Epub 2003 Aug 14. Cancer Immunol Immunother. 2003. PMID: 12827306 Free PMC article.

5

Bryostatin 1/ionomycin (B/I) ex vivo stimulation preferentially activates L-selectinlow tumor-sensitized lymphocytes.

Chin CS, Miller CH, Graham L, Parviz M, Zacur S, Patel B, Duong A, Bear HD. Chin CS, et al. Int Immunol. 2004 Sep;16(9):1283-94. doi: 10.1093/intimm/dxh130. Epub 2004 Jul 19. Int Immunol. 2004. PMID: 15262898

6

Radiofrequency thermal ablation of breast tumors combined with intralesional administration of IL-7 and IL-15 augments anti-tumor immune responses and inhibits tumor development and metastasis.

Habibi M, Kmieciak M, Graham L, Morales JK, Bear HD, Manjili MH. Habibi M, et al. Breast Cancer Res Treat. 2009 Apr;114(3):423-31. doi: 10.1007/s10549-008-0024-3. Epub 2008 Apr 20. Breast Cancer Res Treat. 2009. PMID: 18425677 Free PMC article.

7

Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells.

Morales JK, Kmieciak M, Graham L, Feldmesser M, Bear HD, Manjili MH. Morales JK, et al. Cancer Immunol Immunother. 2009 Jun;58(6):941-53. doi: 10.1007/s00262-008-0609-z. Epub 2008 Nov 1. Cancer Immunol Immunother. 2009. PMID: 18979098 Free PMC article.

8

Incubation of antigen-sensitized T lymphocytes activated with bryostatin 1 + ionomycin in IL-7 + IL-15 increases yield of cells capable of inducing regression of melanoma metastases compared to culture in IL-2.

Le HK, Graham L, Miller CH, Kmieciak M, Manjili MH, Bear HD. Le HK, et al. Cancer Immunol Immunother. 2009 Oct;58(10):1565-76. doi: 10.1007/s00262-009-0666-y. Epub 2009 Feb 6. Cancer Immunol Immunother. 2009. PMID: 19198835 Free PMC article.

9

Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice.

Le HK, Graham L, Cha E, Morales JK, Manjili MH, Bear HD. Le HK, et al. Int Immunopharmacol. 2009 Jul;9(7-8):900-9. doi: 10.1016/j.intimp.2009.03.015. Epub 2009 Mar 29. Int Immunopharmacol. 2009. PMID: 19336265

10

IL-7 + IL-15 are superior to IL-2 for the ex vivo expansion of 4T1 mammary carcinoma-specific T cells with greater efficacy against tumors in vivo.

Cha E, Graham L, Manjili MH, Bear HD. Cha E, et al. Breast Cancer Res Treat. 2010 Jul;122(2):359-69. doi: 10.1007/s10549-009-0573-0. Epub 2009 Oct 14. Breast Cancer Res Treat. 2010. PMID: 19826947 Free PMC article.

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