Maasch C - Search Results

1

Neutralizing Complement C5a Protects Mice with Pneumococcal Pulmonary Sepsis.

Müller-Redetzky H, Kellermann U, Wienhold SM, Gutbier B, Lienau J, Hellwig K, Reppe K, Letsiou E, Tschernig T, Scholz M, Ahnert P, Maasch C, Hoehlig K, Klussmann S, Vater A, Firsching TC, Hoppe J, Suttorp N, Witzenrath M. Müller-Redetzky H, et al. Among authors: maasch c. Anesthesiology. 2020 Apr;132(4):795-807. doi: 10.1097/ALN.0000000000003149. Anesthesiology. 2020. PMID: 32101978 Free article.

2

A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis.

Hoehlig K, Maasch C, Shushakova N, Buchner K, Huber-Lang M, Purschke WG, Vater A, Klussmann S. Hoehlig K, et al. Among authors: maasch c. Mol Ther. 2013 Dec;21(12):2236-46. doi: 10.1038/mt.2013.178. Epub 2013 Jul 26. Mol Ther. 2013. PMID: 23887360 Free PMC article.

3

Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.

Yatime L, Maasch C, Hoehlig K, Klussmann S, Andersen GR, Vater A. Yatime L, et al. Among authors: maasch c. Nat Commun. 2015 Apr 22;6:6481. doi: 10.1038/ncomms7481. Nat Commun. 2015. PMID: 25901944 Free PMC article.

4

A novel CGRP-neutralizing Spiegelmer attenuates neurogenic plasma protein extravasation.

Hoehlig K, Johnson KW, Pryazhnikov E, Maasch C, Clemens-Smith A, Purschke WG, Vauléon S, Buchner K, Jarosch F, Khiroug L, Vater A, Klussmann S. Hoehlig K, et al. Among authors: maasch c. Br J Pharmacol. 2015 Jun;172(12):3086-98. doi: 10.1111/bph.13110. Epub 2015 Mar 27. Br J Pharmacol. 2015. PMID: 25659966 Free PMC article.

5

Polyetheylenimine-polyplexes of Spiegelmer NOX-A50 directed against intracellular high mobility group protein A1 (HMGA1) reduce tumor growth in vivo.

Maasch C, Vater A, Buchner K, Purschke WG, Eulberg D, Vonhoff S, Klussmann S. Maasch C, et al. J Biol Chem. 2010 Dec 17;285(51):40012-8. doi: 10.1074/jbc.M110.178533. Epub 2010 Oct 20. J Biol Chem. 2010. PMID: 20961861 Free PMC article.

6

Development of an automated in vitro selection protocol to obtain RNA-based aptamers: identification of a biostable substance P antagonist.

Eulberg D, Buchner K, Maasch C, Klussmann S. Eulberg D, et al. Among authors: maasch c. Nucleic Acids Res. 2005 Mar 3;33(4):e45. doi: 10.1093/nar/gni044. Nucleic Acids Res. 2005. PMID: 15745995 Free PMC article.

7

Physicochemical stability of NOX-E36, a 40mer L-RNA (Spiegelmer) for therapeutic applications.

Maasch C, Buchner K, Eulberg D, Vonhoff S, Klussmann S. Maasch C, et al. Nucleic Acids Symp Ser (Oxf). 2008;(52):61-2. doi: 10.1093/nass/nrn031. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776253

8

A mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes.

Vater A, Sell S, Kaczmarek P, Maasch C, Buchner K, Pruszynska-Oszmalek E, Kolodziejski P, Purschke WG, Nowak KW, Strowski MZ, Klussmann S. Vater A, et al. Among authors: maasch c. J Biol Chem. 2013 Jul 19;288(29):21136-21147. doi: 10.1074/jbc.M112.444414. Epub 2013 Jun 6. J Biol Chem. 2013. PMID: 23744070 Free PMC article.

9

Targeting complement component 5a promotes vascular integrity and limits airway remodeling.

Khan MA, Maasch C, Vater A, Klussmann S, Morser J, Leung LL, Atkinson C, Tomlinson S, Heeger PS, Nicolls MR. Khan MA, et al. Among authors: maasch c. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6061-6. doi: 10.1073/pnas.1217991110. Epub 2013 Mar 25. Proc Natl Acad Sci U S A. 2013. PMID: 23530212 Free PMC article.

10

Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.

Oberthür D, Achenbach J, Gabdulkhakov A, Buchner K, Maasch C, Falke S, Rehders D, Klussmann S, Betzel C. Oberthür D, et al. Among authors: maasch c. Nat Commun. 2015 Apr 22;6:6923. doi: 10.1038/ncomms7923. Nat Commun. 2015. PMID: 25901662 Free PMC article.

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