Ghosh G - Search Results

1

Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics.

Ngo KA, Kishimoto K, Davis-Turak J, Pimplaskar A, Cheng Z, Spreafico R, Chen EY, Tam A, Ghosh G, Mitchell S, Hoffmann A. Ngo KA, et al. Among authors: ghosh g. Cell Rep. 2020 Feb 25;30(8):2758-2775.e6. doi: 10.1016/j.celrep.2020.01.108. Cell Rep. 2020. PMID: 32101750 Free PMC article.

2

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation.

Huxford T, Huang DB, Malek S, Ghosh G. Huxford T, et al. Among authors: ghosh g. Cell. 1998 Dec 11;95(6):759-70. doi: 10.1016/s0092-8674(00)81699-2. Cell. 1998. PMID: 9865694 Free article.

3

A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation.

Sanjabi S, Williams KJ, Saccani S, Zhou L, Hoffmann A, Ghosh G, Gerondakis S, Natoli G, Smale ST. Sanjabi S, et al. Among authors: ghosh g. Genes Dev. 2005 Sep 15;19(18):2138-51. doi: 10.1101/gad.1329805. Genes Dev. 2005. PMID: 16166378 Free PMC article.

4

Transcriptional regulation via the NF-kappaB signaling module.

Hoffmann A, Natoli G, Ghosh G. Hoffmann A, et al. Among authors: ghosh g. Oncogene. 2006 Oct 30;25(51):6706-16. doi: 10.1038/sj.onc.1209933. Oncogene. 2006. PMID: 17072323 Review.

5

A fourth IkappaB protein within the NF-kappaB signaling module.

Basak S, Kim H, Kearns JD, Tergaonkar V, O'Dea E, Werner SL, Benedict CA, Ware CF, Ghosh G, Verma IM, Hoffmann A. Basak S, et al. Among authors: ghosh g. Cell. 2007 Jan 26;128(2):369-81. doi: 10.1016/j.cell.2006.12.033. Cell. 2007. PMID: 17254973 Free PMC article.

6

Stabilization of RelB requires multidomain interactions with p100/p52.

Fusco AJ, Savinova OV, Talwar R, Kearns JD, Hoffmann A, Ghosh G. Fusco AJ, et al. Among authors: ghosh g. J Biol Chem. 2008 May 2;283(18):12324-32. doi: 10.1074/jbc.M707898200. Epub 2008 Mar 4. J Biol Chem. 2008. PMID: 18321863 Free PMC article.

7

NF-kappaB dictates the degradation pathway of IkappaBalpha.

Mathes E, O'Dea EL, Hoffmann A, Ghosh G. Mathes E, et al. Among authors: ghosh g. EMBO J. 2008 May 7;27(9):1357-67. doi: 10.1038/emboj.2008.73. Epub 2008 Apr 10. EMBO J. 2008. PMID: 18401342 Free PMC article.

8

Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity.

Shih VF, Kearns JD, Basak S, Savinova OV, Ghosh G, Hoffmann A. Shih VF, et al. Among authors: ghosh g. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9619-24. doi: 10.1073/pnas.0812367106. Epub 2009 Jun 1. Proc Natl Acad Sci U S A. 2009. PMID: 19487661 Free PMC article.

9

The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes.

Savinova OV, Hoffmann A, Ghosh G. Savinova OV, et al. Among authors: ghosh g. Mol Cell. 2009 Jun 12;34(5):591-602. doi: 10.1016/j.molcel.2009.04.033. Mol Cell. 2009. PMID: 19524538 Free PMC article.

10

Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha.

Bergqvist S, Alverdi V, Mengel B, Hoffmann A, Ghosh G, Komives EA. Bergqvist S, et al. Among authors: ghosh g. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19328-33. doi: 10.1073/pnas.0908797106. Epub 2009 Nov 3. Proc Natl Acad Sci U S A. 2009. PMID: 19887633 Free PMC article.

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