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Loss of low-molecular-weight protein tyrosine phosphatase shows limited improvement in glucose tolerance but causes mild cardiac hypertrophy in mice.
Jensen-Cody S, Coyne ES, Ding X, Sebin A, Vogel J, Goldstein J, Rosahl TW, Zhou HH, Jacobs H, Champy MF, About GB, Talukdar S, Zhou Y. Jensen-Cody S, et al. Among authors: talukdar s. Am J Physiol Endocrinol Metab. 2022 Jun 1;322(6):E517-E527. doi: 10.1152/ajpendo.00161.2021. Epub 2022 Apr 11. Am J Physiol Endocrinol Metab. 2022. PMID: 35403438 Free article.
Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease.
Smith GI, Shankaran M, Yoshino M, Schweitzer GG, Chondronikola M, Beals JW, Okunade AL, Patterson BW, Nyangau E, Field T, Sirlin CB, Talukdar S, Hellerstein MK, Klein S. Smith GI, et al. Among authors: talukdar s. J Clin Invest. 2020 Mar 2;130(3):1453-1460. doi: 10.1172/JCI134165. J Clin Invest. 2020. PMID: 31805015 Free PMC article. Clinical Trial.
Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing.
Weng Y, Ishino T, Sievers A, Talukdar S, Chabot JR, Tam A, Duan W, Kerns K, Sousa E, He T, Logan A, Lee D, Li D, Zhou Y, Bernardo B, Joyce A, Kavosi M, O'Hara DM, Clark T, Guo J, Giragossian C, Stahl M, Calle RA, Kriz R, Somers W, Lin L. Weng Y, et al. Among authors: talukdar s. Sci Rep. 2018 Mar 9;8(1):4241. doi: 10.1038/s41598-018-22456-w. Sci Rep. 2018. PMID: 29523796 Free PMC article.
Mapping Lipogenic Flux: A Gold LDI-MS Approach for Imaging Neutral Lipid Kinetics.
Downes DP, Zhong W, Zhang J, Chen B, Satapati S, Metzger D, Godinez G, Lao J, Sheth PR, McLaren DG, Talukdar S, Previs SF. Downes DP, et al. Among authors: talukdar s. J Am Soc Mass Spectrom. 2020 Dec 2;31(12):2421-2425. doi: 10.1021/jasms.0c00199. Epub 2020 Sep 1. J Am Soc Mass Spectrom. 2020. PMID: 32840373
Discovery of a new class of integrin antibodies for fibrosis.
Zhang J, Wang T, Saigal A, Johnson J, Morrisson J, Tabrizifard S, Hollingsworth SA, Eddins MJ, Mao W, O'Neill K, Garcia-Calvo M, Carballo-Jane E, Liu D, Ham T, Zhou Q, Dong W, Meng HW, Hicks J, Cai TQ, Akiyama T, Pinto S, Cheng AC, Greshock T, Marquis JC, Ren Z, Talukdar S, Shaheen HH, Handa M. Zhang J, et al. Among authors: talukdar s. Sci Rep. 2021 Jan 22;11(1):2118. doi: 10.1038/s41598-021-81253-0. Sci Rep. 2021. PMID: 33483531 Free PMC article.
FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis.
Mottillo EP, Desjardins EM, Fritzen AM, Zou VZ, Crane JD, Yabut JM, Kiens B, Erion DM, Lanba A, Granneman JG, Talukdar S, Steinberg GR. Mottillo EP, et al. Among authors: talukdar s. Mol Metab. 2017 Apr 5;6(6):471-481. doi: 10.1016/j.molmet.2017.04.001. eCollection 2017 Jun. Mol Metab. 2017. PMID: 28580278 Free PMC article.
237 results