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Page 1
The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants.
Rio-Machin A, Vulliamy T, Hug N, Walne A, Tawana K, Cardoso S, Ellison A, Pontikos N, Wang J, Tummala H, Al Seraihi AFH, Alnajar J, Bewicke-Copley F, Armes H, Barnett M, Bloor A, Bödör C, Bowen D, Fenaux P, Green A, Hallahan A, Hjorth-Hansen H, Hossain U, Killick S, Lawson S, Layton M, Male AM, Marsh J, Mehta P, Mous R, Nomdedéu JF, Owen C, Pavlu J, Payne EM, Protheroe RE, Preudhomme C, Pujol-Moix N, Renneville A, Russell N, Saggar A, Sciuccati G, Taussig D, Toze CL, Uyttebroeck A, Vandenberghe P, Schlegelberger B, Ripperger T, Steinemann D, Wu J, Mason J, Page P, Akiki S, Reay K, Cavenagh JD, Plagnol V, Caceres JF, Fitzgibbon J, Dokal I. Rio-Machin A, et al. Among authors: layton m. Nat Commun. 2020 Feb 25;11(1):1044. doi: 10.1038/s41467-020-14829-5. Nat Commun. 2020. PMID: 32098966 Free PMC article.
Sickle cell disease: the case for coordinated information.
Streetly A, Dick M, Layton M. Streetly A, et al. Among authors: layton m. BMJ. 1993 Jun 5;306(6891):1491-2. doi: 10.1136/bmj.306.6891.1491. BMJ. 1993. PMID: 8518672 Free PMC article. No abstract available.
Analgesia and peripheral c-fiber modulation by selective Nav1.8 inhibition in rhesus.
Vardigan JD, Pall PS, McDevitt DS, Huang C, Clements MK, Li Y, Kraus RL, Breslin MJ, Bungard CJ, Nemenov MI, Klukinov M, Burgey CS, Layton ME, Stachel SJ, Lange HS, Savitz AT, Santarelli VP, Henze DA, Uslaner JM. Vardigan JD, et al. Among authors: layton me. Pain. 2024 Oct 8. doi: 10.1097/j.pain.0000000000003404. Online ahead of print. Pain. 2024. PMID: 39382325
Glucose levels at hospital admission are associated with 5 year mortality.
Cheung NW, McElduff P, Fulcher G, Middleton S, Chen R, Depczynski B, Flack J, Kinsella J, Layton M, McLean M, Poynten A, Tonks K, White C, Wong V, Chipps DR. Cheung NW, et al. Among authors: layton m. Diabetes Res Clin Pract. 2024 Nov;217:111840. doi: 10.1016/j.diabres.2024.111840. Epub 2024 Aug 30. Diabetes Res Clin Pract. 2024. PMID: 39216794
Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling.
Alvarez N, Adam GC, Howe JA, Sharma V, Zimmerman MD, Dolgov E, Rasheed R, Nizar F, Sahay K, Nelson AM, Park S, Zhou X, Burlein C, Fay JF, Iwamoto DV, Bahnck-Teets CM, Getty KL, Lin Goh S, Salhab I, Smith K, Boyce CW, Cabalu TD, Murgolo N, Fox NG, Mayhood TW, Shurtleff VW, Layton ME, Parish CA, McCauley JA, Olsen DB, Perlin DS. Alvarez N, et al. Among authors: layton me. Viruses. 2024 Jul 18;16(7):1158. doi: 10.3390/v16071158. Viruses. 2024. PMID: 39066320 Free PMC article.
Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.
Shurtleff VW, Layton ME, Parish CA, Perkins JJ, Schreier JD, Wang Y, Adam GC, Alvarez N, Bahmanjah S, Bahnck-Teets CM, Boyce CW, Burlein C, Cabalu TD, Campbell BT, Carroll SS, Chang W, de Lera Ruiz M, Dolgov E, Fay JF, Fox NG, Goh SL, Hartingh TJ, Hurzy DM, Kelly MJ 3rd, Klein DJ, Klingler FM, Krishnamurthy H, Kudalkar S, Mayhood TW, McKenna PM, Murray EM, Nahas D, Nawrat CC, Park S, Qian D, Roecker AJ, Sharma V, Shipe WD, Su J, Taggart RV, Truong Q, Wu Y, Zhou X, Zhuang N, Perlin DS, Olsen DB, Howe JA, McCauley JA. Shurtleff VW, et al. Among authors: layton me. J Med Chem. 2024 Mar 14;67(5):3935-3958. doi: 10.1021/acs.jmedchem.3c02248. Epub 2024 Feb 16. J Med Chem. 2024. PMID: 38365209
320 results