Groenen PMA - Search Results

1

Traditional and Digital Biomarkers: Two Worlds Apart?

Babrak LM, Menetski J, Rebhan M, Nisato G, Zinggeler M, Brasier N, Baerenfaller K, Brenzikofer T, Baltzer L, Vogler C, Gschwind L, Schneider C, Streiff F, Groenen PMA, Miho E. Babrak LM, et al. Among authors: groenen pma. Digit Biomark. 2019 Aug 16;3(2):92-102. doi: 10.1159/000502000. eCollection 2019 May-Aug. Digit Biomark. 2019. PMID: 32095769 Free PMC article.

2

Remote digital monitoring in clinical trials in the time of COVID-19.

Goldsack JC, Izmailova ES, Menetski JP, Hoffmann SC, Groenen PMA, Wagner JA. Goldsack JC, et al. Among authors: groenen pma. Nat Rev Drug Discov. 2020 Jun;19(6):378-379. doi: 10.1038/d41573-020-00094-0. Nat Rev Drug Discov. 2020. PMID: 32409759 No abstract available.

3

Assessment of Peripheral Serotonin Synthesis Using Stable Isotope-Labeled Tryptophan.

Gehin M, Welford RWD, Garzotti M, Vercauteren M, Groenen PMA, Nayler O, Sidharta PN, Dingemanse J. Gehin M, et al. Among authors: groenen pma. Clin Pharmacol Ther. 2018 Dec;104(6):1260-1267. doi: 10.1002/cpt.1087. Epub 2018 May 10. Clin Pharmacol Ther. 2018. PMID: 29663345

4

Preclinical to clinical translation of cenerimod, a novel S1P₁ receptor modulator, in systemic lupus erythematosus.

Strasser DS, Froidevaux S, Sippel V, Gerossier E, Grieder U, Pierlot GM, Kieninger-Graefitsch A, Vezzali E, Stalder AK, Renault B, Ryge J, Hart A, Mentzel U, Groenen PMA, Keller MP, Trendelenburg M, Martinic MM, Murphy MJ. Strasser DS, et al. Among authors: groenen pma. RMD Open. 2020 Sep;6(2):e001261. doi: 10.1136/rmdopen-2020-001261. RMD Open. 2020. PMID: 32917831 Free PMC article.

5

A molecular view of amyotrophic lateral sclerosis through the lens of interaction network modules.

Jensen KH, Stalder AK, Wernersson R, Roloff-Handschin TC, Hansen DH, Groenen PMA. Jensen KH, et al. Among authors: groenen pma. PLoS One. 2022 May 16;17(5):e0268159. doi: 10.1371/journal.pone.0268159. eCollection 2022. PLoS One. 2022. PMID: 35576218 Free PMC article.

6

A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects.

Géhin M, Strasser DS, Zisowsky J, Farine H, Groenen PM, Dingemanse J, Sidharta PN. Géhin M, et al. J Clin Pharmacol. 2015 Jul;55(7):787-97. doi: 10.1002/jcph.478. Epub 2015 Mar 30. J Clin Pharmacol. 2015. PMID: 25655470 Clinical Trial.

7

Eosinophilic oesophagitis: relevance of mast cell infiltration.

Strasser DS, Seger S, Bussmann C, Pierlot GM, Groenen PMA, Stalder AK, Straumann A. Strasser DS, et al. Among authors: groenen pma. Histopathology. 2018 Sep;73(3):454-463. doi: 10.1111/his.13653. Epub 2018 Jun 22. Histopathology. 2018. PMID: 29772120

8

Serotonin biosynthesis as a predictive marker of serotonin pharmacodynamics and disease-induced dysregulation.

Welford RW, Vercauteren M, Trébaul A, Cattaneo C, Eckert D, Garzotti M, Sieber P, Segrestaa J, Studer R, Groenen PM, Nayler O. Welford RW, et al. Sci Rep. 2016 Jul 21;6:30059. doi: 10.1038/srep30059. Sci Rep. 2016. PMID: 27444653 Free PMC article.

9

Biomarker-guided clinical development of the first-in-class anti-inflammatory FPR2/ALX agonist ACT-389949.

Stalder AK, Lott D, Strasser DS, Cruz HG, Krause A, Groenen PM, Dingemanse J. Stalder AK, et al. Br J Clin Pharmacol. 2017 Mar;83(3):476-486. doi: 10.1111/bcp.13149. Epub 2016 Nov 15. Br J Clin Pharmacol. 2017. PMID: 27730665 Free PMC article. Clinical Trial.

10

Multiple-ascending doses of ACT-1014-6470, an oral complement factor 5a receptor 1 (C5a₁ receptor) antagonist: Tolerability, pharmacokinetics and target engagement.

Anliker-Ort M, Dingemanse J, Farine H, Groenen P, Kornberger R, van den Anker J, Kaufmann P. Anliker-Ort M, et al. Br J Clin Pharmacol. 2023 Jan;89(1):380-389. doi: 10.1111/bcp.15508. Epub 2022 Sep 7. Br J Clin Pharmacol. 2023. PMID: 36000981 Free article. Clinical Trial.

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