Roberts AJ - Search Results

1

Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion.

Zhao WN, Tobe BTD, Udeshi ND, Xuan LL, Pernia CD, Zolg DP, Roberts AJ, Mani D, Blumenthal SR, Kurtser I, Patnaik D, Gaisina I, Bishop J, Sheridan SD, Lalonde J, Carr SA, Snyder EY, Haggarty SJ. Zhao WN, et al. Among authors: roberts aj. Transl Psychiatry. 2020 Feb 24;10(1):76. doi: 10.1038/s41398-020-0753-6. Transl Psychiatry. 2020. PMID: 32094324 Free PMC article.

2

A Upf3b-mutant mouse model with behavioral and neurogenesis defects.

Huang L, Shum EY, Jones SH, Lou CH, Chousal J, Kim H, Roberts AJ, Jolly LA, Espinoza JL, Skarbrevik DM, Phan MH, Cook-Andersen H, Swerdlow NR, Gecz J, Wilkinson MF. Huang L, et al. Among authors: roberts aj. Mol Psychiatry. 2018 Aug;23(8):1773-1786. doi: 10.1038/mp.2017.173. Epub 2017 Sep 26. Mol Psychiatry. 2018. PMID: 28948974 Free PMC article.

3

Selecting for neurogenic potential as an alternative for Alzheimer's disease drug discovery.

Prior M, Goldberg J, Chiruta C, Farrokhi C, Kopynets M, Roberts AJ, Schubert D. Prior M, et al. Among authors: roberts aj. Alzheimers Dement. 2016 Jun;12(6):678-86. doi: 10.1016/j.jalz.2016.03.016. Epub 2016 May 2. Alzheimers Dement. 2016. PMID: 27149904 Free PMC article.

4

Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model.

Lordén G, Wozniak JM, Doré K, Dozier LE, Cates-Gatto C, Patrick GN, Gonzalez DJ, Roberts AJ, Tanzi RE, Newton AC. Lordén G, et al. Among authors: roberts aj. Nat Commun. 2022 Nov 23;13(1):7200. doi: 10.1038/s41467-022-34679-7. Nat Commun. 2022. PMID: 36418293 Free PMC article.

5

IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase.

Dugan LL, Ali SS, Shekhtman G, Roberts AJ, Lucero J, Quick KL, Behrens MM. Dugan LL, et al. Among authors: roberts aj. PLoS One. 2009;4(5):e5518. doi: 10.1371/journal.pone.0005518. Epub 2009 May 13. PLoS One. 2009. PMID: 19436757 Free PMC article.

6

A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease.

Chen Q, Prior M, Dargusch R, Roberts A, Riek R, Eichmann C, Chiruta C, Akaishi T, Abe K, Maher P, Schubert D. Chen Q, et al. PLoS One. 2011;6(12):e27865. doi: 10.1371/journal.pone.0027865. Epub 2011 Dec 14. PLoS One. 2011. PMID: 22194796 Free PMC article.

7

Evaluation of TLR4 Inhibitor, T5342126, in Modulation of Ethanol-Drinking Behavior in Alcohol-Dependent Mice.

Bajo M, Montgomery SE, Cates LN, Nadav T, Delucchi AM, Cheng K, Yin H, Crawford EF, Roberts AJ, Roberto M. Bajo M, et al. Among authors: roberts aj. Alcohol Alcohol. 2016 Sep;51(5):541-8. doi: 10.1093/alcalc/agw026. Epub 2016 May 5. Alcohol Alcohol. 2016. PMID: 27151970 Free PMC article.

8

ImAge quantitates aging and rejuvenation.

Alvarez-Kuglen M, Ninomiya K, Qin H, Rodriguez D, Fiengo L, Farhy C, Hsu WM, Kirk B, Havas A, Feng GS, Roberts AJ, Anderson RM, Serrano M, Adams PD, Sharpee TO, Terskikh AV. Alvarez-Kuglen M, et al. Among authors: roberts aj. Nat Aging. 2024 Sep;4(9):1308-1327. doi: 10.1038/s43587-024-00685-1. Epub 2024 Aug 29. Nat Aging. 2024. PMID: 39210148

9

γ-Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Countered Alzheimer-Related Pathologies in a Mouse Model of Down Syndrome.

Chen XQ, Becker A, Albay R, Nguyen PD, Karachentsev D, Roberts AJ, Rynearson KD, Tanzi RE, Mobley WC. Chen XQ, et al. Among authors: roberts aj. Ann Neurol. 2024 Aug;96(2):390-404. doi: 10.1002/ana.26958. Epub 2024 May 15. Ann Neurol. 2024. PMID: 38747498

10

Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport.

Carmona MA, Murai KK, Wang L, Roberts AJ, Pasquale EB. Carmona MA, et al. Among authors: roberts aj. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12524-9. doi: 10.1073/pnas.0903328106. Epub 2009 Jul 10. Proc Natl Acad Sci U S A. 2009. PMID: 19592509 Free PMC article.

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