Jin J - Search Results

1

Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain.

Xiong J, Jin J, Gao L, Hao C, Liu X, Liu BF, Chen Y, Zhang G. Xiong J, et al. Among authors: jin j. Eur J Med Chem. 2020 Apr 1;191:112144. doi: 10.1016/j.ejmech.2020.112144. Epub 2020 Feb 14. Eur J Med Chem. 2020. PMID: 32087465

2

Discovery of 3-aryl-4-isoxazolecarboxamides as TGR5 receptor agonists.

Evans KA, Budzik BW, Ross SA, Wisnoski DD, Jin J, Rivero RA, Vimal M, Szewczyk GR, Jayawickreme C, Moncol DL, Rimele TJ, Armour SL, Weaver SP, Griffin RJ, Tadepalli SM, Jeune MR, Shearer TW, Chen ZB, Chen L, Anderson DL, Becherer JD, De Los Frailes M, Colilla FJ. Evans KA, et al. Among authors: jin j. J Med Chem. 2009 Dec 24;52(24):7962-5. doi: 10.1021/jm901434t. J Med Chem. 2009. PMID: 19902954

3

Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice.

Korboukh I, Hull-Ryde EA, Rittiner JE, Randhawa AS, Coleman J, Fitzpatrick BJ, Setola V, Janzen WP, Frye SV, Zylka MJ, Jin J. Korboukh I, et al. Among authors: jin j. J Med Chem. 2012 Jul 26;55(14):6467-77. doi: 10.1021/jm3004834. Epub 2012 Jul 16. J Med Chem. 2012. PMID: 22738238 Free PMC article.

4

Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists.

Chen X, McCorvy JD, Fischer MG, Butler KV, Shen Y, Roth BL, Jin J. Chen X, et al. Among authors: jin j. J Med Chem. 2016 Dec 8;59(23):10601-10618. doi: 10.1021/acs.jmedchem.6b01208. Epub 2016 Nov 16. J Med Chem. 2016. PMID: 27805392 Free PMC article.

5

Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D₁ Receptor Agonists.

Martini ML, Liu J, Ray C, Yu X, Huang XP, Urs A, Urs N, McCorvy JD, Caron MG, Roth BL, Jin J. Martini ML, et al. Among authors: jin j. J Med Chem. 2019 Apr 11;62(7):3753-3772. doi: 10.1021/acs.jmedchem.9b00351. Epub 2019 Mar 27. J Med Chem. 2019. PMID: 30875219 Free PMC article.

6

D₂ Dopamine Receptor G Protein-Biased Partial Agonists Based on Cariprazine.

Shen Y, McCorvy JD, Martini ML, Rodriguiz RM, Pogorelov VM, Ward KM, Wetsel WC, Liu J, Roth BL, Jin J. Shen Y, et al. Among authors: jin j. J Med Chem. 2019 May 9;62(9):4755-4771. doi: 10.1021/acs.jmedchem.9b00508. Epub 2019 Apr 18. J Med Chem. 2019. PMID: 30964661 Free PMC article.

7

Polymorphs of DP-VPA Solid Solutions and Their Physicochemical Properties.

Hao C, Jin J, Xiong J, Yang Z, Gao L, Ma Y, Liu BF, Liu X, Chen Y, Zhang G. Hao C, et al. Among authors: jin j. J Pharm Sci. 2020 Jul;109(7):2156-2165. doi: 10.1016/j.xphs.2020.03.017. Epub 2020 Mar 30. J Pharm Sci. 2020. PMID: 32240697

8

Polymorphs and pharmacokinetics of an antipsychotic drug candidate.

Hao C, Chen Y, Xiong J, Yang Z, Gao L, Liu BF, Liu X, Jin J, Zhang G. Hao C, et al. Among authors: jin j. Int J Pharm. 2020 Aug 30;586:119600. doi: 10.1016/j.ijpharm.2020.119600. Epub 2020 Jul 3. Int J Pharm. 2020. PMID: 32629070

9

Isoquinolinone derivatives as potent CNS multi-receptor D₂/5-HT_1A/5-HT_2A/5-HT₆/5-HT₇ agents: Synthesis and pharmacological evaluation.

Jin J, Zhang K, Dou F, Hao C, Zhang Y, Cao X, Gao L, Xiong J, Liu X, Liu BF, Zhang G, Chen Y. Jin J, et al. Eur J Med Chem. 2020 Dec 1;207:112709. doi: 10.1016/j.ejmech.2020.112709. Epub 2020 Aug 20. Eur J Med Chem. 2020. PMID: 32877805

10

Design, Synthesis and Biological Investigation of Flavone Derivatives as Potential Multi-Receptor Atypical Antipsychotics.

Gao L, Yang Z, Xiong J, Hao C, Ma R, Liu X, Liu BF, Jin J, Zhang G, Chen Y. Gao L, et al. Among authors: jin j. Molecules. 2020 Sep 8;25(18):4107. doi: 10.3390/molecules25184107. Molecules. 2020. PMID: 32911828 Free PMC article.

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