Sicheri F - Search Results

1

Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids.

Wiechmann S, Maisonneuve P, Grebbin BM, Hoffmeister M, Kaulich M, Clevers H, Rajalingam K, Kurinov I, Farin HF, Sicheri F, Ernst A. Wiechmann S, et al. Among authors: sicheri f. J Biol Chem. 2020 Apr 3;295(14):4526-4540. doi: 10.1074/jbc.RA119.011025. Epub 2020 Feb 20. J Biol Chem. 2020. PMID: 32086379 Free PMC article.

2

Non-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9.

Ceccarelli DF, Blasutig IM, Goudreault M, Li Z, Ruston J, Pawson T, Sicheri F. Ceccarelli DF, et al. Among authors: sicheri f. J Biol Chem. 2007 May 4;282(18):13864-74. doi: 10.1074/jbc.M700505200. Epub 2007 Mar 5. J Biol Chem. 2007. PMID: 17339315 Free article.

3

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.

Rajakulendran T, Sahmi M, Kurinov I, Tyers M, Therrien M, Sicheri F. Rajakulendran T, et al. Among authors: sicheri f. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2836-41. doi: 10.1073/pnas.0709705105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287031 Free PMC article.

4

Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.

Mao DY, Neculai D, Downey M, Orlicky S, Haffani YZ, Ceccarelli DF, Ho JS, Szilard RK, Zhang W, Ho CS, Wan L, Fares C, Rumpel S, Kurinov I, Arrowsmith CH, Durocher D, Sicheri F. Mao DY, et al. Among authors: sicheri f. Mol Cell. 2008 Oct 24;32(2):259-75. doi: 10.1016/j.molcel.2008.10.002. Mol Cell. 2008. PMID: 18951093 Free PMC article.

5

A dimerization-dependent mechanism drives RAF catalytic activation.

Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien M. Rajakulendran T, et al. Among authors: sicheri f. Nature. 2009 Sep 24;461(7263):542-5. doi: 10.1038/nature08314. Epub 2009 Sep 2. Nature. 2009. PMID: 19727074

6

The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates.

Ogunjimi AA, Wiesner S, Briant DJ, Varelas X, Sicheri F, Forman-Kay J, Wrana JL. Ogunjimi AA, et al. Among authors: sicheri f. J Biol Chem. 2010 Feb 26;285(9):6308-15. doi: 10.1074/jbc.M109.044537. Epub 2009 Dec 21. J Biol Chem. 2010. PMID: 20026602 Free PMC article.

7

Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization.

Kean MJ, Ceccarelli DF, Goudreault M, Sanches M, Tate S, Larsen B, Gibson LC, Derry WB, Scott IC, Pelletier L, Baillie GS, Sicheri F, Gingras AC. Kean MJ, et al. Among authors: sicheri f. J Biol Chem. 2011 Jul 15;286(28):25065-75. doi: 10.1074/jbc.M110.214486. Epub 2011 May 11. J Biol Chem. 2011. PMID: 21561862 Free PMC article.

8

CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization.

Ceccarelli DF, Laister RC, Mulligan VK, Kean MJ, Goudreault M, Scott IC, Derry WB, Chakrabartty A, Gingras AC, Sicheri F. Ceccarelli DF, et al. Among authors: sicheri f. J Biol Chem. 2011 Jul 15;286(28):25056-64. doi: 10.1074/jbc.M110.213777. Epub 2011 May 11. J Biol Chem. 2011. PMID: 21561863 Free PMC article.

9

Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.

Wan LC, Mao DY, Neculai D, Strecker J, Chiovitti D, Kurinov I, Poda G, Thevakumaran N, Yuan F, Szilard RK, Lissina E, Nislow C, Caudy AA, Durocher D, Sicheri F. Wan LC, et al. Among authors: sicheri f. Nucleic Acids Res. 2013 Jul;41(12):6332-46. doi: 10.1093/nar/gkt322. Epub 2013 Apr 25. Nucleic Acids Res. 2013. PMID: 23620299 Free PMC article.

10

Structural basis for the recruitment of glycogen synthase by glycogenin.

Zeqiraj E, Tang X, Hunter RW, García-Rocha M, Judd A, Deak M, von Wilamowitz-Moellendorff A, Kurinov I, Guinovart JJ, Tyers M, Sakamoto K, Sicheri F. Zeqiraj E, et al. Among authors: sicheri f. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2831-40. doi: 10.1073/pnas.1402926111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982189 Free PMC article.

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