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Page 1
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.
Jarret A, Jackson R, Duizer C, Healy ME, Zhao J, Rone JM, Bielecki P, Sefik E, Roulis M, Rice T, Sivanathan KN, Zhou T, Solis AG, Honcharova-Biletska H, Vélez K, Hartner S, Low JS, Qu R, de Zoete MR, Palm NW, Ring AM, Weber A, Moor AE, Kluger Y, Nowarski R, Flavell RA. Jarret A, et al. Among authors: sefik e. Cell. 2020 Feb 20;180(4):813-814. doi: 10.1016/j.cell.2020.02.004. Cell. 2020. PMID: 32084342 Free article. No abstract available.
m6A mRNA methylation sustains Treg suppressive functions.
Tong J, Cao G, Zhang T, Sefik E, Amezcua Vesely MC, Broughton JP, Zhu S, Li H, Li B, Chen L, Chang HY, Su B, Flavell RA, Li HB. Tong J, et al. Among authors: sefik e. Cell Res. 2018 Feb;28(2):253-256. doi: 10.1038/cr.2018.7. Epub 2018 Jan 5. Cell Res. 2018. PMID: 29303144 Free PMC article. No abstract available.
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.
Jarret A, Jackson R, Duizer C, Healy ME, Zhao J, Rone JM, Bielecki P, Sefik E, Roulis M, Rice T, Sivanathan KN, Zhou T, Solis AG, Honcharova-Biletska H, Vélez K, Hartner S, Low JS, Qu R, de Zoete MR, Palm NW, Ring AM, Weber A, Moor AE, Kluger Y, Nowarski R, Flavell RA. Jarret A, et al. Among authors: sefik e. Cell. 2020 Jan 9;180(1):50-63.e12. doi: 10.1016/j.cell.2019.12.016. Cell. 2020. PMID: 31923399 Free PMC article.
A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options.
Sefik E, Israelow B, Zhao J, Qu R, Song E, Mirza H, Kaffe E, Halene S, Meffre E, Kluger Y, Nussenzweig M, Wilen CB, Iwasaki A, Flavell RA. Sefik E, et al. Res Sq [Preprint]. 2021 Mar 17:rs.3.rs-279341. doi: 10.21203/rs.3.rs-279341/v1. Res Sq. 2021. Update in: Nat Biotechnol. 2022 Jun;40(6):906-920. doi: 10.1038/s41587-021-01155-4 PMID: 33758831 Free PMC article. Updated. Preprint.
Detection of differentially abundant cell subpopulations in scRNA-seq data.
Zhao J, Jaffe A, Li H, Lindenbaum O, Sefik E, Jackson R, Cheng X, Flavell RA, Kluger Y. Zhao J, et al. Among authors: sefik e. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2100293118. doi: 10.1073/pnas.2100293118. Proc Natl Acad Sci U S A. 2021. PMID: 34001664 Free PMC article.
A humanized mouse model of chronic COVID-19.
Sefik E, Israelow B, Mirza H, Zhao J, Qu R, Kaffe E, Song E, Halene S, Meffre E, Kluger Y, Nussenzweig M, Wilen CB, Iwasaki A, Flavell RA. Sefik E, et al. Nat Biotechnol. 2022 Jun;40(6):906-920. doi: 10.1038/s41587-021-01155-4. Epub 2021 Dec 17. Nat Biotechnol. 2022. PMID: 34921308 Free PMC article.
Human neutrophil development and functionality are enabled in a humanized mouse model.
Zheng Y, Sefik E, Astle J, Karatepe K, Öz HH, Solis AG, Jackson R, Luo HR, Bruscia EM, Halene S, Shan L, Flavell RA. Zheng Y, et al. Among authors: sefik e. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2121077119. doi: 10.1073/pnas.2121077119. Epub 2022 Oct 21. Proc Natl Acad Sci U S A. 2022. PMID: 36269862 Free PMC article.
Gene trajectory inference for single-cell data by optimal transport metrics.
Qu R, Cheng X, Sefik E, Stanley Iii JS, Landa B, Strino F, Platt S, Garritano J, Odell ID, Coifman R, Flavell RA, Myung P, Kluger Y. Qu R, et al. Among authors: sefik e. Nat Biotechnol. 2024 Apr 5:10.1038/s41587-024-02186-3. doi: 10.1038/s41587-024-02186-3. Online ahead of print. Nat Biotechnol. 2024. PMID: 38580861
83 results