Liang X - Search Results

1

Structurally novel PI3Kδ/γ dual inhibitors characterized by a seven-membered spirocyclic spacer: The SARs investigation and PK evaluation.

Tao Q, Chen Y, Liang X, Hu Y, Li J, Fang F, Wang H, Meng C, Liang J, Ma X, Gui S. Tao Q, et al. Among authors: liang x, liang j. Eur J Med Chem. 2020 Apr 1;191:112143. doi: 10.1016/j.ejmech.2020.112143. Epub 2020 Feb 17. Eur J Med Chem. 2020. PMID: 32078865

2

Discovery of novel 2-aryl-3-sulfonamido-pyridines (HoAns) as microtubule polymerization inhibitors with potent antitumor activities.

Zhu H, Ying S, Zhou B, Liang X, He Q, Song P, Hu X, Shi K, Xiong M, Jin H, Pan Y. Zhu H, et al. Among authors: liang x. Eur J Med Chem. 2021 Feb 5;211:113117. doi: 10.1016/j.ejmech.2020.113117. Epub 2020 Dec 25. Eur J Med Chem. 2021. PMID: 33360794

3

Pueraria flavones-loaded bile salt liposomes with improved intestinal absorption and oral bioavailability: in vitro and in vivo evaluation.

Tang M, Gui Z, Liang X, Yan C, Li X, Li Z, He N, Chang X, Guo J, Gui S. Tang M, et al. Among authors: liang x. Pharm Dev Technol. 2021 Dec;26(10):1051-1060. doi: 10.1080/10837450.2021.1980010. Epub 2021 Oct 5. Pharm Dev Technol. 2021. PMID: 34511044

4

Sorafenib-Loaded PLGA-TPGS Nanosystems Enhance Hepatocellular Carcinoma Therapy Through Reversing P-Glycoprotein-Mediated Multidrug Resistance.

Tang M, Huang Y, Liang X, Tao Y, He N, Li Z, Guo J, Gui S. Tang M, et al. Among authors: liang x. AAPS PharmSciTech. 2022 Apr 29;23(5):130. doi: 10.1208/s12249-022-02214-y. AAPS PharmSciTech. 2022. PMID: 35487999

5

Polyvinylpyrrolidone microneedles for localized delivery of sinomenine hydrochloride: preparation, release behavior of in vitro & in vivo, and penetration mechanism.

Shu Z, Cao Y, Tao Y, Liang X, Wang F, Li Z, Li Z, Gui S. Shu Z, et al. Among authors: liang x. Drug Deliv. 2020 Dec;27(1):642-651. doi: 10.1080/10717544.2020.1754524. Drug Deliv. 2020. PMID: 32329377 Free PMC article.

6

The discovery of indole derivatives as novel hepatitis C virus inhibitors.

Han Z, Liang X, Wang Y, Qing J, Cao L, Shang L, Yin Z. Han Z, et al. Among authors: liang x. Eur J Med Chem. 2016 Jun 30;116:147-155. doi: 10.1016/j.ejmech.2016.03.062. Epub 2016 Mar 26. Eur J Med Chem. 2016. PMID: 27061978

7

Additives-directed lyotropic liquid crystals architecture: Simulations and experiments.

Wang K, Li Z, Huang Y, YaotianTao, Liang X, Chu X, He N, Gui S, Li Z. Wang K, et al. Among authors: liang x. Int J Pharm. 2021 May 1;600:120353. doi: 10.1016/j.ijpharm.2021.120353. Epub 2021 Feb 4. Int J Pharm. 2021. PMID: 33549811

8

Design, synthesis, and evaluation of novel coumarin-dithiocarbamate derivatives (IDs) as anti-colorectal cancer agents.

Zhu H, Ying S, Zhou B, Hu X, Liang X, Li W, Wang D, Jin H, Pan Y. Zhu H, et al. Among authors: liang x. J Enzyme Inhib Med Chem. 2021 Dec;36(1):593-604. doi: 10.1080/14756366.2021.1875458. J Enzyme Inhib Med Chem. 2021. PMID: 33557648 Free PMC article.

9

Inhibition of striatal-enriched protein tyrosine phosphatase by targeting computationally revealed cryptic pockets.

Hou X, Sun JP, Ge L, Liang X, Li K, Zhang Y, Fang H. Hou X, et al. Among authors: liang x. Eur J Med Chem. 2020 Mar 15;190:112131. doi: 10.1016/j.ejmech.2020.112131. Epub 2020 Feb 11. Eur J Med Chem. 2020. PMID: 32078861 Free PMC article.

10

Design, synthesis and biological evaluation of imidazolidine-2,4-dione and 2-thioxothiazolidin-4-one derivatives as lymphoid-specific tyrosine phosphatase inhibitors.

Liang X, Fu H, Xiao P, Fang H, Hou X. Liang X, et al. Bioorg Chem. 2020 Oct;103:104124. doi: 10.1016/j.bioorg.2020.104124. Epub 2020 Jul 23. Bioorg Chem. 2020. PMID: 32768742

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