Li J - Search Results

1

Structurally novel PI3Kδ/γ dual inhibitors characterized by a seven-membered spirocyclic spacer: The SARs investigation and PK evaluation.

Tao Q, Chen Y, Liang X, Hu Y, Li J, Fang F, Wang H, Meng C, Liang J, Ma X, Gui S. Tao Q, et al. Among authors: li j. Eur J Med Chem. 2020 Apr 1;191:112143. doi: 10.1016/j.ejmech.2020.112143. Epub 2020 Feb 17. Eur J Med Chem. 2020. PMID: 32078865

2

Synthesis and evaluation of salicylanilide derivatives as potential epidermal growth factor receptor inhibitors.

Hu M, Ye W, Li J, Zhong G, He G, Xu Q, Zhang Y. Hu M, et al. Among authors: li j. Chem Biol Drug Des. 2015 Mar;85(3):280-9. doi: 10.1111/cbdd.12383. Epub 2014 Sep 2. Chem Biol Drug Des. 2015. PMID: 24954438

3

Design, synthesis, and biological evaluation of novel tetrahydroisoquinoline derivatives as potential antitumor candidate.

Zhu P, Ye W, Li J, Zhang Y, Huang W, Cheng M, Wang Y, Zhang Y, Liu H, Zuo J. Zhu P, et al. Among authors: li j. Chem Biol Drug Des. 2017 Mar;89(3):443-455. doi: 10.1111/cbdd.12873. Epub 2016 Nov 10. Chem Biol Drug Des. 2017. PMID: 27717183

4

Design, synthesis, and evaluation of genipin derivatives for the treatment of Alzheimer's Disease.

Huang W, Wang Y, Li J, Zhang Y, Ma X, Zhu P, Zhang Y. Huang W, et al. Among authors: li j. Chem Biol Drug Des. 2019 Feb;93(2):110-122. doi: 10.1111/cbdd.13194. Epub 2018 Nov 28. Chem Biol Drug Des. 2019. PMID: 29543387

5

Design, synthesis chalcone derivatives as AdipoR agonist for type 2 diabetes.

Zhu P, Huang W, Li J, Ma X, Hu M, Wang Y, Xu Q, Wang X. Zhu P, et al. Among authors: li j. Chem Biol Drug Des. 2018 Aug;92(2):1525-1536. doi: 10.1111/cbdd.13319. Epub 2018 May 30. Chem Biol Drug Des. 2018. PMID: 29704399

6

[Design, synthesis, and biological evaluation of phenylpropenamides compounds as anti-platelet aggregation].

Yang Y, Zuo J, Li JM, Ma XD, Zhang YC, Huang WJ. Yang Y, et al. Among authors: li jm. Yao Xue Xue Bao. 2017 Jan;52(1):120-5. Yao Xue Xue Bao. 2017. PMID: 29911807 Chinese.

7

Discovery of traditional Chinese medicine monomers and their synthetic intermediates, analogs or derivatives for battling P-gp-mediated multi-drug resistance.

Ma X, Hu M, Wang H, Li J. Ma X, et al. Among authors: li j. Eur J Med Chem. 2018 Nov 5;159:381-392. doi: 10.1016/j.ejmech.2018.09.061. Epub 2018 Sep 26. Eur J Med Chem. 2018. PMID: 30308411 Review.

8

Design, synthesis, and biological evaluation of tetrahydroisoquinoline-based diaryl urea derivatives for suppressing VEGFR-2 signaling.

Huang Y, Zhang Y, Li J, Ma X, Hu M, Yang Y, Gao S. Huang Y, et al. Among authors: li j. Anticancer Drugs. 2019 Jun;30(5):508-516. doi: 10.1097/CAD.0000000000000718. Anticancer Drugs. 2019. PMID: 30531369

9

Conformationally restricted quinazolone derivatives as PI3Kδ-selective inhibitors: the design, synthesis and biological evaluation.

Ma X, Fang F, Tao Q, Shen L, Zhong G, Qiao T, Lv X, Li J. Ma X, et al. Among authors: li j. Medchemcomm. 2019 Jan 23;10(3):413-420. doi: 10.1039/c8md00556g. eCollection 2019 Mar 1. Medchemcomm. 2019. PMID: 30996859 Free PMC article.

10

Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.

Huang Y, Zhang B, Li J, Liu H, Zhang Y, Yang Z, Liu W. Huang Y, et al. Among authors: li j. Eur J Med Chem. 2019 Oct 15;180:41-50. doi: 10.1016/j.ejmech.2019.07.004. Epub 2019 Jul 4. Eur J Med Chem. 2019. PMID: 31299586

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