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A novel Alzheimer disease locus located near the gene encoding tau protein.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH Jr, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L; IGAP Consortium; Haines JL, Psaty B… See abstract for full author list ➔ Jun G, et al. Mol Psychiatry. 2016 Jan;21(1):108-17. doi: 10.1038/mp.2015.23. Epub 2015 Mar 17. Mol Psychiatry. 2016. PMID: 25778476 Free PMC article.
Neurofilament light chain in the vitreous humor of the eye.
Subramanian ML, Vig V, Chung J, Fiorello MG, Xia W, Zetterberg H, Blennow K, Zetterberg M, Shareef F, Siegel NH, Ness S, Jun GR, Stein TD. Subramanian ML, et al. Among authors: jun gr. Alzheimers Res Ther. 2020 Sep 17;12(1):111. doi: 10.1186/s13195-020-00677-4. Alzheimers Res Ther. 2020. PMID: 32943089 Free PMC article.
Cytokine Levels in Human Vitreous in Proliferative Diabetic Retinopathy.
Loporchio DF, Tam EK, Cho J, Chung J, Jun GR, Xia W, Fiorello MG, Siegel NH, Ness S, Stein TD, Subramanian ML. Loporchio DF, et al. Among authors: jun gr. Cells. 2021 Apr 30;10(5):1069. doi: 10.3390/cells10051069. Cells. 2021. PMID: 33946446 Free PMC article.
Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau.
Frank B, Ally M, Brekke B, Zetterberg H, Blennow K, Sugarman MA, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkina I, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Jun GR, Kowall NW, Stein TD, McKee AC, Killiany R, Qiu WQ, Stern RA, Mez J, Alosco ML. Frank B, et al. Among authors: jun gr. Alzheimers Dement. 2022 Aug;18(8):1523-1536. doi: 10.1002/alz.12508. Epub 2021 Dec 2. Alzheimers Dement. 2022. PMID: 34854549 Free PMC article.
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease.
Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W; Alzheimer's Disease Genetics Consortium; Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Au R, Lunetta KL, Ikezu T, Stein TD, Farrer LA. Jun GR, et al. Alzheimers Dement. 2022 Nov;18(11):2042-2054. doi: 10.1002/alz.12607. Epub 2022 Feb 9. Alzheimers Dement. 2022. PMID: 35142023 Free PMC article.
Ante-mortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy.
Morrison MS, Aparicio HJ, Blennow K, Zetterberg H, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Sugarman MA, Frank B, Steinberg EG, Turk KW, Budson AE, Au R, Goldstein LE, Jun GR, Kowall NW, Killiany R, Qiu WQ, Stern RA, Mez J, McKee AC, Stein TD, Alosco ML. Morrison MS, et al. Among authors: jun gr. Brain. 2022 Oct 21;145(10):3546-3557. doi: 10.1093/brain/awac175. Brain. 2022. PMID: 35554506 Free PMC article.
309 results