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Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints.
Molkentine JM, Molkentine DP, Bridges KA, Xie T, Yang L, Sheth A, Heffernan TP, Clump DA, Faust AZ, Ferris RL, Myers JN, Frederick MJ, Mason KA, Meyn RE, Pickering CR, Skinner HD. Molkentine JM, et al. Among authors: meyn re. Int J Radiat Biol. 2021;97(8):1121-1128. doi: 10.1080/09553002.2020.1730014. Epub 2020 Feb 25. Int J Radiat Biol. 2021. PMID: 32073931 Free PMC article.
Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer.
Skinner HD, Giri U, Yang L, Woo SH, Story MD, Pickering CR, Byers LA, Williams MD, El-Naggar A, Wang J, Diao L, Shen L, Fan YH, Molkentine DP, Beadle BM, Meyn RE, Myers JN, Heymach JV. Skinner HD, et al. Among authors: meyn re. Clin Cancer Res. 2016 Sep 15;22(18):4643-50. doi: 10.1158/1078-0432.CCR-15-2785. Epub 2016 Apr 1. Clin Cancer Res. 2016. PMID: 27036135 Free PMC article.
p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade.
Molkentine DP, Molkentine JM, Bridges KA, Valdecanas DR, Dhawan A, Bahri R, Hefner AJ, Kumar M, Yang L, Abdelhakiem M, Pifer PM, Sandulache V, Sheth A, Beadle BM, Thames HD, Mason KA, Pickering CR, Meyn RE, Skinner HD. Molkentine DP, et al. Among authors: meyn re. Cancer Res. 2022 Mar 1;82(5):916-928. doi: 10.1158/0008-5472.CAN-21-2101. Cancer Res. 2022. PMID: 34965932 Free PMC article.
Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence.
Osman AA, Monroe MM, Ortega Alves MV, Patel AA, Katsonis P, Fitzgerald AL, Neskey DM, Frederick MJ, Woo SH, Caulin C, Hsu TK, McDonald TO, Kimmel M, Meyn RE, Lichtarge O, Myers JN. Osman AA, et al. Among authors: meyn re. Mol Cancer Ther. 2015 Feb;14(2):608-19. doi: 10.1158/1535-7163.MCT-14-0735-T. Epub 2014 Dec 10. Mol Cancer Ther. 2015. PMID: 25504633 Free PMC article.
180 results