Somanath PR - Search Results

1

Delayed Akt suppression in the lipopolysaccharide-induced acute lung injury promotes resolution that is associated with enhanced effector regulatory T cells.

Artham S, Verma A, Alwhaibi A, Adil MS, Manicassamy S, Munn DH, Somanath PR. Artham S, et al. Among authors: somanath pr. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L750-L761. doi: 10.1152/ajplung.00251.2019. Epub 2020 Feb 19. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32073894 Free PMC article.

2

TGFβ- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR).

Goc A, Choudhary M, Byzova TV, Somanath PR. Goc A, et al. Among authors: somanath pr. J Cell Physiol. 2011 Nov;226(11):3004-13. doi: 10.1002/jcp.22648. J Cell Physiol. 2011. PMID: 21302298 Free PMC article.

3

TNFα induces inflammatory stress response in microvascular endothelial cells via Akt- and P38 MAP kinase-mediated thrombospondin-1 expression.

Fairaq A, Goc A, Artham S, Sabbineni H, Somanath PR. Fairaq A, et al. Among authors: somanath pr. Mol Cell Biochem. 2015 Aug;406(1-2):227-36. doi: 10.1007/s11010-015-2440-0. Epub 2015 May 12. Mol Cell Biochem. 2015. PMID: 25963668 Free PMC article.

4

The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGFβ-induced pulmonary fibrosis.

Abdalla M, Sabbineni H, Prakash R, Ergul A, Fagan SC, Somanath PR. Abdalla M, et al. Among authors: somanath pr. Br J Pharmacol. 2015 Aug;172(16):4173-88. doi: 10.1111/bph.13203. Epub 2015 Jul 6. Br J Pharmacol. 2015. PMID: 26033700 Free PMC article.

5

Genetic deletion and pharmacological inhibition of Akt1 isoform attenuates bladder cancer cell proliferation, motility and invasion.

Sabbineni H, Alwhaibi A, Goc A, Gao F, Pruitt A, Somanath PR. Sabbineni H, et al. Among authors: somanath pr. Eur J Pharmacol. 2015 Oct 5;764:208-214. doi: 10.1016/j.ejphar.2015.06.059. Epub 2015 Jul 3. Eur J Pharmacol. 2015. PMID: 26148825 Free PMC article.

6

Akt1 promotes stimuli-induced endothelial-barrier protection through FoxO-mediated tight-junction protein turnover.

Gao F, Artham S, Sabbineni H, Al-Azayzih A, Peng XD, Hay N, Adams RH, Byzova TV, Somanath PR. Gao F, et al. Among authors: somanath pr. Cell Mol Life Sci. 2016 Oct;73(20):3917-33. doi: 10.1007/s00018-016-2232-z. Epub 2016 Apr 25. Cell Mol Life Sci. 2016. PMID: 27113546 Free PMC article.

7

Modulation of long-term endothelial-barrier integrity is conditional to the cross-talk between Akt and Src signaling.

Gao F, Sabbineni H, Artham S, Somanath PR. Gao F, et al. Among authors: somanath pr. J Cell Physiol. 2017 Oct;232(10):2599-2609. doi: 10.1002/jcp.25791. Epub 2017 Feb 9. J Cell Physiol. 2017. PMID: 28075016 Free PMC article.

8

Suppression of Akt1-β-catenin pathway in advanced prostate cancer promotes TGFβ1-mediated epithelial to mesenchymal transition and metastasis.

Gao F, Alwhaibi A, Sabbineni H, Verma A, Eldahshan W, Somanath PR. Gao F, et al. Among authors: somanath pr. Cancer Lett. 2017 Aug 28;402:177-189. doi: 10.1016/j.canlet.2017.05.028. Epub 2017 Jun 7. Cancer Lett. 2017. PMID: 28602980 Free PMC article.

9

Lack of adequate pneumococcal vaccination response in chronic lymphocytic leukaemia patients receiving ibrutinib.

Andrick B, Alwhaibi A, DeRemer DL, Quershi S, Khan R, Bryan LJ, Somanath PR, Pantin J. Andrick B, et al. Among authors: somanath pr. Br J Haematol. 2018 Sep;182(5):712-714. doi: 10.1111/bjh.14855. Epub 2017 Jul 24. Br J Haematol. 2018. PMID: 28737280 Free article. No abstract available.

10

Endothelial Akt1 loss promotes prostate cancer metastasis via β-catenin-regulated tight-junction protein turnover.

Gao F, Alwhaibi A, Artham S, Verma A, Somanath PR. Gao F, et al. Among authors: somanath pr. Br J Cancer. 2018 May;118(11):1464-1475. doi: 10.1038/s41416-018-0110-1. Epub 2018 May 14. Br J Cancer. 2018. PMID: 29755115 Free PMC article.

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