Alwhaibi A - Search Results

1

Delayed Akt suppression in the lipopolysaccharide-induced acute lung injury promotes resolution that is associated with enhanced effector regulatory T cells.

Artham S, Verma A, Alwhaibi A, Adil MS, Manicassamy S, Munn DH, Somanath PR. Artham S, et al. Among authors: alwhaibi a. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L750-L761. doi: 10.1152/ajplung.00251.2019. Epub 2020 Feb 19. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32073894 Free PMC article.

2

Endothelial stromelysin1 regulation by the forkhead box-O transcription factors is crucial in the exudative phase of acute lung injury.

Artham S, Gao F, Verma A, Alwhaibi A, Sabbineni H, Hafez S, Ergul A, Somanath PR. Artham S, et al. Among authors: alwhaibi a. Pharmacol Res. 2019 Mar;141:249-263. doi: 10.1016/j.phrs.2019.01.006. Epub 2019 Jan 3. Pharmacol Res. 2019. PMID: 30611853 Free PMC article.

3

Genetic deletion and pharmacological inhibition of Akt1 isoform attenuates bladder cancer cell proliferation, motility and invasion.

Sabbineni H, Alwhaibi A, Goc A, Gao F, Pruitt A, Somanath PR. Sabbineni H, et al. Among authors: alwhaibi a. Eur J Pharmacol. 2015 Oct 5;764:208-214. doi: 10.1016/j.ejphar.2015.06.059. Epub 2015 Jul 3. Eur J Pharmacol. 2015. PMID: 26148825 Free PMC article.

4

Suppression of Akt1-β-catenin pathway in advanced prostate cancer promotes TGFβ1-mediated epithelial to mesenchymal transition and metastasis.

Gao F, Alwhaibi A, Sabbineni H, Verma A, Eldahshan W, Somanath PR. Gao F, et al. Among authors: alwhaibi a. Cancer Lett. 2017 Aug 28;402:177-189. doi: 10.1016/j.canlet.2017.05.028. Epub 2017 Jun 7. Cancer Lett. 2017. PMID: 28602980 Free PMC article.

5

Endothelial Akt1 loss promotes prostate cancer metastasis via β-catenin-regulated tight-junction protein turnover.

Gao F, Alwhaibi A, Artham S, Verma A, Somanath PR. Gao F, et al. Among authors: alwhaibi a. Br J Cancer. 2018 May;118(11):1464-1475. doi: 10.1038/s41416-018-0110-1. Epub 2018 May 14. Br J Cancer. 2018. PMID: 29755115 Free PMC article.

6

Modulation in the microRNA repertoire is responsible for the stage-specific effects of Akt suppression on murine neuroendocrine prostate cancer.

Alwhaibi A, Gao F, Artham S, Hsia BM, Mondal A, Kolhe R, Somanath PR. Alwhaibi A, et al. Heliyon. 2018 Sep 17;4(9):e00796. doi: 10.1016/j.heliyon.2018.e00796. eCollection 2018 Sep. Heliyon. 2018. PMID: 30238065 Free PMC article.

7

The unconventional role of Akt1 in the advanced cancers and in diabetes-promoted carcinogenesis.

Alwhaibi A, Verma A, Adil MS, Somanath PR. Alwhaibi A, et al. Pharmacol Res. 2019 Jul;145:104270. doi: 10.1016/j.phrs.2019.104270. Epub 2019 May 9. Pharmacol Res. 2019. PMID: 31078742 Free PMC article. Review.

8

Nodal pathway activation due to Akt1 suppression is a molecular switch for prostate cancer cell epithelial-to-mesenchymal transition and metastasis.

Alwhaibi A, Verma A, Artham S, Adil MS, Somanath PR. Alwhaibi A, et al. Biochem Pharmacol. 2019 Oct;168:1-13. doi: 10.1016/j.bcp.2019.06.010. Epub 2019 Jun 14. Biochem Pharmacol. 2019. PMID: 31202735 Free PMC article.

9

Genome atlas analysis based profiling of Akt pathway genes in the early and advanced human prostate cancer.

Alwhaibi A, Kolhe R, Gao F, Cobran EK, Somanath PR. Alwhaibi A, et al. Oncoscience. 2019 Jul 2;6(5-6):317-336. doi: 10.18632/oncoscience.482. eCollection 2019 May. Oncoscience. 2019. PMID: 31360736 Free PMC article.

10

PAK1 inhibitor IPA-3 mitigates metastatic prostate cancer-induced bone remodeling.

Verma A, Artham S, Alwhaibi A, Adil MS, Cummings BS, Somanath PR. Verma A, et al. Among authors: alwhaibi a. Biochem Pharmacol. 2020 Jul;177:113943. doi: 10.1016/j.bcp.2020.113943. Epub 2020 Mar 30. Biochem Pharmacol. 2020. PMID: 32240651 Free PMC article.

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