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Page 1
Establishment of a Monoclonal Antibody That Recognizes Cysteine-Rich Domain 1 of Human CD271.
Morita S, Mochizuki M, Shibuya-Takahashi R, Nakamura-Shima M, Yamazaki T, Imai T, Asada Y, Matsuura K, Kawamura S, Yamaguchi K, Yasuda J, Sugamura K, Katori Y, Satoh K, Tamai K. Morita S, et al. Among authors: nakamura shima m. Monoclon Antib Immunodiagn Immunother. 2020 Feb;39(1):6-11. doi: 10.1089/mab.2019.0040. Monoclon Antib Immunodiagn Immunother. 2020. PMID: 32069133
BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma.
Tamai K, Nakamura-Shima M, Shibuya-Takahashi R, Kanno SI, Yasui A, Mochizuki M, Iwai W, Wakui Y, Abue M, Yamamoto K, Miura K, Mizuma M, Unno M, Kawamura S, Sato I, Yasuda J, Yamaguchi K, Sugamura K, Satoh K. Tamai K, et al. Among authors: nakamura shima m. Sci Rep. 2020 Dec 9;10(1):21592. doi: 10.1038/s41598-020-78539-0. Sci Rep. 2020. PMID: 33299012 Free PMC article.
Discovery of a chemical compound that suppresses expression of BEX2, a dormant cancer stem cell-related protein.
Saijoh S, Nakamura-Shima M, Shibuya-Takahashi R, Ito R, Sugawara A, Yamazaki T, Imai T, Asada Y, Matsuura K, Iwai W, Wakui Y, Abue M, Kawamura S, Katayose Y, Fujimori H, Mochizuki M, Yasuda J, Yamaguchi K, Sugamura K, Satoh K, Katori Y, Tamai K. Saijoh S, et al. Among authors: nakamura shima m. Biochem Biophys Res Commun. 2021 Jan 22;537:132-139. doi: 10.1016/j.bbrc.2020.11.022. Epub 2021 Jan 4. Biochem Biophys Res Commun. 2021. PMID: 33412384
Delta-6 desaturase FADS2 is a tumor-promoting factor in cholangiocarcinoma.
Hasegawa K, Fujimori H, Nakatani K, Takahashi M, Izumi Y, Bamba T, Nakamura-Shima M, Shibuya-Takahashi R, Mochizuki M, Wakui Y, Abue M, Iwai W, Fukushi D, Satoh K, Yamaguchi K, Shindo N, Yasuda J, Asano N, Imai T, Asada Y, Katori Y, Tamai K. Hasegawa K, et al. Among authors: nakamura shima m. Cancer Sci. 2024 Oct;115(10):3346-3357. doi: 10.1111/cas.16306. Epub 2024 Aug 7. Cancer Sci. 2024. PMID: 39113435 Free PMC article.
BEX2 is poor prognostic factor and required for cancer stemness in gastric cancer.
Yasumoto A, Fujimori H, Mochizuki M, Shibuya-Takahashi R, Nakamura-Shima M, Shindo N, Yamaguchi K, Fukushi D, Wakui Y, Sugai T, Iwai W, Abue M, Sato I, Satoh K, Katayose Y, Yasuda J, Shibata C, Tamai K. Yasumoto A, et al. Among authors: nakamura shima m. Biochem Biophys Res Commun. 2023 May 7;655:59-67. doi: 10.1016/j.bbrc.2023.03.025. Epub 2023 Mar 11. Biochem Biophys Res Commun. 2023. PMID: 36933308