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Page 1
Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis.
Kanwar N, Carmine-Simmen K, Nair R, Wang C, Moghadas-Jafari S, Blaser H, Tran-Thanh D, Wang D, Wang P, Wang J, Pasculescu A, Datti A, Mak T, Lewis JD, Done SJ. Kanwar N, et al. Among authors: carmine simmen k. EBioMedicine. 2020 Feb;52:102646. doi: 10.1016/j.ebiom.2020.102646. Epub 2020 Feb 12. EBioMedicine. 2020. PMID: 32062352 Free PMC article.
Endothelial Cell mTOR Complex-2 Regulates Sprouting Angiogenesis.
Farhan MA, Carmine-Simmen K, Lewis JD, Moore RB, Murray AG. Farhan MA, et al. Among authors: carmine simmen k. PLoS One. 2015 Aug 21;10(8):e0135245. doi: 10.1371/journal.pone.0135245. eCollection 2015. PLoS One. 2015. PMID: 26295809 Free PMC article.
Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis.
Leong HS, Robertson AE, Stoletov K, Leith SJ, Chin CA, Chien AE, Hague MN, Ablack A, Carmine-Simmen K, McPherson VA, Postenka CO, Turley EA, Courtneidge SA, Chambers AF, Lewis JD. Leong HS, et al. Among authors: carmine simmen k. Cell Rep. 2014 Sep 11;8(5):1558-70. doi: 10.1016/j.celrep.2014.07.050. Epub 2014 Aug 28. Cell Rep. 2014. PMID: 25176655 Free article.
Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase.
Kinnaird A, Dromparis P, Saleme B, Gurtu V, Watson K, Paulin R, Zervopoulos S, Stenson T, Sutendra G, Pink DB, Carmine-Simmen K, Moore R, Lewis JD, Michelakis ED. Kinnaird A, et al. Among authors: carmine simmen k. Eur Urol. 2016 Apr;69(4):734-744. doi: 10.1016/j.eururo.2015.09.014. Epub 2016 Feb 18. Eur Urol. 2016. PMID: 26433571
The subcellular distribution of calnexin is mediated by PACS-2.
Myhill N, Lynes EM, Nanji JA, Blagoveshchenskaya AD, Fei H, Carmine Simmen K, Cooper TJ, Thomas G, Simmen T. Myhill N, et al. Mol Biol Cell. 2008 Jul;19(7):2777-88. doi: 10.1091/mbc.e07-10-0995. Epub 2008 Apr 16. Mol Biol Cell. 2008. PMID: 18417615 Free PMC article.
Design and characterization of a novel human Granzyme B inhibitor.
Marcet-Palacios M, Ewen C, Pittman E, Duggan B, Carmine-Simmen K, Fahlman RP, Bleackley RC. Marcet-Palacios M, et al. Among authors: carmine simmen k. Protein Eng Des Sel. 2015 Jan;28(1):9-17. doi: 10.1093/protein/gzu052. Epub 2014 Dec 9. Protein Eng Des Sel. 2015. PMID: 25492933
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