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JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function.
Sci Transl Med. 2020 Feb 12;12(530):eaay4447. doi: 10.1126/scitranslmed.aay4447.
Sci Transl Med. 2020.
PMID: 32051226
PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass.
Müller DIH, Stoll C, Palumbo-Zerr K, Böhm C, Krishnacoumar B, Ipseiz N, Taubmann J, Zimmermann M, Böttcher M, Mougiakakos D, Tuckermann J, Djouad F, Schett G, Scholtysek C, Krönke G.
Müller DIH, et al.
Sci Rep. 2020 May 21;10(1):8428. doi: 10.1038/s41598-020-65305-5.
Sci Rep. 2020.
PMID: 32439961
Free PMC article.
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Metabolic reprogramming of osteoclasts represents a therapeutic target during the treatment of osteoporosis.
Taubmann J, Krishnacoumar B, Böhm C, Faas M, Müller DIH, Adam S, Stoll C, Böttcher M, Mougiakakos D, Sonnewald U, Hofmann J, Schett G, Krönke G, Scholtysek C.
Taubmann J, et al. Among authors: muller dih.
Sci Rep. 2020 Dec 3;10(1):21020. doi: 10.1038/s41598-020-77892-4.
Sci Rep. 2020.
PMID: 33273570
Free PMC article.
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[Practical Ultrasound Skills in Medical School].
Müller D, Strobel D.
Müller D, et al.
Praxis (Bern 1994). 2018 Nov;107(23):1261-1265. doi: 10.1024/1661-8157/a003113.
Praxis (Bern 1994). 2018.
PMID: 30424690
German.
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