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Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes.
Ginn SL, Amaya AK, Liao SHY, Zhu E, Cunningham SC, Lee M, Hallwirth CV, Logan GJ, Tay SS, Cesare AJ, Pickett HA, Grompe M, Dilworth K, Lisowski L, Alexander IE. Ginn SL, et al. Among authors: tay ss. JHEP Rep. 2019 Dec 27;2(1):100065. doi: 10.1016/j.jhepr.2019.100065. eCollection 2020 Feb. JHEP Rep. 2019. PMID: 32039406 Free PMC article.
Adeno-associated virus serotypes for gene therapeutics.
Lisowski L, Tay SS, Alexander IE. Lisowski L, et al. Among authors: tay ss. Curr Opin Pharmacol. 2015 Oct;24:59-67. doi: 10.1016/j.coph.2015.07.006. Epub 2015 Aug 25. Curr Opin Pharmacol. 2015. PMID: 26291407 Review.
Limiting Thymic Precursor Supply Increases the Risk of Lymphoid Malignancy in Murine X-Linked Severe Combined Immunodeficiency.
Ginn SL, Hallwirth CV, Liao SHY, Teber ET, Arthur JW, Wu J, Lee HC, Tay SS, Hu M, Reddel RR, McCormack MP, Thrasher AJ, Cavazzana M, Alexander SI, Alexander IE. Ginn SL, et al. Among authors: tay ss. Mol Ther Nucleic Acids. 2017 Mar 17;6:1-14. doi: 10.1016/j.omtn.2016.11.011. Epub 2016 Dec 10. Mol Ther Nucleic Acids. 2017. PMID: 28325276 Free PMC article.
Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction.
Paul-Heng M, Leong M, Cunningham E, Bunker DLJ, Bremner K, Wang Z, Wang C, Tay SS, McGuffog C, Logan GJ, Alexander IE, Hu M, Alexander SI, Sparwasser TD, Bertolino P, Bowen DG, Bishop GA, Sharland A. Paul-Heng M, et al. Among authors: tay ss. JCI Insight. 2018 Aug 9;3(15):e97500. doi: 10.1172/jci.insight.97500. eCollection 2018 Aug 9. JCI Insight. 2018. PMID: 30089715 Free PMC article.
Gene therapy for tolerance: high-level expression of donor major histocompatibility complex in the liver overcomes naive and memory alloresponses to skin grafts.
Cunningham EC, Tay SS, Wang C, Rtshiladze M, Wang ZZ, McGuffog C, Cubitt J, McCaughan GW, Alexander IE, Bertolino P, Sharland AF, Bowen DG, Bishop GA. Cunningham EC, et al. Among authors: tay ss. Transplantation. 2013 Jan 15;95(1):70-7. doi: 10.1097/TP.0b013e318278d39a. Transplantation. 2013. PMID: 23263501
Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells.
Tay SS, Wong YC, Roediger B, Sierro F, Lu B, McDonald DM, McGuffog CM, Meyer NJ, Alexander IE, Parish IA, Heath WR, Weninger W, Bishop GA, Gamble JR, McCaughan GW, Bertolino P, Bowen DG. Tay SS, et al. J Immunol. 2014 Sep 1;193(5):2087-95. doi: 10.4049/jimmunol.1400037. Epub 2014 Jul 28. J Immunol. 2014. PMID: 25070847
An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis.
Roediger B, Lee Q, Tikoo S, Cobbin JCA, Henderson JM, Jormakka M, O'Rourke MB, Padula MP, Pinello N, Henry M, Wynne M, Santagostino SF, Brayton CF, Rasmussen L, Lisowski L, Tay SS, Harris DC, Bertram JF, Dowling JP, Bertolino P, Lai JH, Wu W, Bachovchin WW, Wong JJ, Gorrell MD, Shaban B, Holmes EC, Jolly CJ, Monette S, Weninger W. Roediger B, et al. Among authors: tay ss. Cell. 2018 Oct 4;175(2):530-543.e24. doi: 10.1016/j.cell.2018.08.013. Epub 2018 Sep 13. Cell. 2018. PMID: 30220458 Free PMC article.
170 results