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Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes.
Ginn SL, Amaya AK, Liao SHY, Zhu E, Cunningham SC, Lee M, Hallwirth CV, Logan GJ, Tay SS, Cesare AJ, Pickett HA, Grompe M, Dilworth K, Lisowski L, Alexander IE. Ginn SL, et al. Among authors: grompe m. JHEP Rep. 2019 Dec 27;2(1):100065. doi: 10.1016/j.jhepr.2019.100065. eCollection 2020 Feb. JHEP Rep. 2019. PMID: 32039406 Free PMC article.
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Paulk NK, et al. Among authors: grompe m. Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25. Mol Ther. 2018. PMID: 29055620 Free PMC article.
AAV integration in human hepatocytes.
Dalwadi DA, Calabria A, Tiyaboonchai A, Posey J, Naugler WE, Montini E, Grompe M. Dalwadi DA, et al. Among authors: grompe m. Mol Ther. 2021 Oct 6;29(10):2898-2909. doi: 10.1016/j.ymthe.2021.08.031. Epub 2021 Aug 28. Mol Ther. 2021. PMID: 34461297 Free PMC article.
Cell fusion is the principal source of bone-marrow-derived hepatocytes.
Wang X, Willenbring H, Akkari Y, Torimaru Y, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Olson S, Grompe M. Wang X, et al. Among authors: grompe m. Nature. 2003 Apr 24;422(6934):897-901. doi: 10.1038/nature01531. Epub 2003 Mar 30. Nature. 2003. PMID: 12665832
Rapid in vivo multiplexed editing (RIME) of the adult mouse liver.
Katsuda T, Cure H, Sussman J, Simeonov KP, Krapp C, Arany Z, Grompe M, Stanger BZ. Katsuda T, et al. Among authors: grompe m. Hepatology. 2023 Aug 1;78(2):486-502. doi: 10.1002/hep.32759. Epub 2022 Oct 13. Hepatology. 2023. PMID: 36037289 Free PMC article.
281 results