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APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid.
Zhao N, Attrebi ON, Ren Y, Qiao W, Sonustun B, Martens YA, Meneses AD, Li F, Shue F, Zheng J, Van Ingelgom AJ, Davis MD, Kurti A, Knight JA, Linares C, Chen Y, Delenclos M, Liu CC, Fryer JD, Asmann YW, McLean PJ, Dickson DW, Ross OA, Bu G. Zhao N, et al. Sci Transl Med. 2020 Feb 5;12(529):eaay1809. doi: 10.1126/scitranslmed.aay1809. Sci Transl Med. 2020. PMID: 32024798 Free PMC article.
Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.
Shinohara M, Murray ME, Frank RD, Shinohara M, DeTure M, Yamazaki Y, Tachibana M, Atagi Y, Davis MD, Liu CC, Zhao N, Painter MM, Petersen RC, Fryer JD, Crook JE, Dickson DW, Bu G, Kanekiyo T. Shinohara M, et al. Among authors: zhao n. Acta Neuropathol. 2016 Aug;132(2):225-234. doi: 10.1007/s00401-016-1580-y. Epub 2016 May 14. Acta Neuropathol. 2016. PMID: 27179972 Free PMC article.
ApoE4 Accelerates Early Seeding of Amyloid Pathology.
Liu CC, Zhao N, Fu Y, Wang N, Linares C, Tsai CW, Bu G. Liu CC, et al. Among authors: zhao n. Neuron. 2017 Dec 6;96(5):1024-1032.e3. doi: 10.1016/j.neuron.2017.11.013. Neuron. 2017. PMID: 29216449 Free PMC article.
APOE ε2 is associated with increased tau pathology in primary tauopathy.
Zhao N, Liu CC, Van Ingelgom AJ, Linares C, Kurti A, Knight JA, Heckman MG, Diehl NN, Shinohara M, Martens YA, Attrebi ON, Petrucelli L, Fryer JD, Wszolek ZK, Graff-Radford NR, Caselli RJ, Sanchez-Contreras MY, Rademakers R, Murray ME, Koga S, Dickson DW, Ross OA, Bu G. Zhao N, et al. Nat Commun. 2018 Oct 22;9(1):4388. doi: 10.1038/s41467-018-06783-0. Nat Commun. 2018. PMID: 30348994 Free PMC article.
5,420 results