Chandra A - Search Results

1

Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss.

Chandra A, Lagnado AB, Farr JN, Monroe DG, Park S, Hachfeld C, Tchkonia T, Kirkland JL, Khosla S, Passos JF, Pignolo RJ. Chandra A, et al. J Bone Miner Res. 2020 Jun;35(6):1119-1131. doi: 10.1002/jbmr.3978. Epub 2020 Mar 5. J Bone Miner Res. 2020. PMID: 32023351 Free PMC article.

2

PTH1-34 alleviates radiotherapy-induced local bone loss by improving osteoblast and osteocyte survival.

Chandra A, Lin T, Tribble MB, Zhu J, Altman AR, Tseng WJ, Zhang Y, Akintoye SO, Cengel K, Liu XS, Qin L. Chandra A, et al. Bone. 2014 Oct;67:33-40. doi: 10.1016/j.bone.2014.06.030. Epub 2014 Jul 1. Bone. 2014. PMID: 24998454 Free PMC article.

3

Suppression of Sclerostin Alleviates Radiation-Induced Bone Loss by Protecting Bone-Forming Cells and Their Progenitors Through Distinct Mechanisms.

Chandra A, Lin T, Young T, Tong W, Ma X, Tseng WJ, Kramer I, Kneissel M, Levine MA, Zhang Y, Cengel K, Liu XS, Qin L. Chandra A, et al. J Bone Miner Res. 2017 Feb;32(2):360-372. doi: 10.1002/jbmr.2996. Epub 2016 Oct 20. J Bone Miner Res. 2017. PMID: 27635523 Free PMC article.

4

IL15RA is required for osteoblast function and bone mineralization.

Loro E, Ramaswamy G, Chandra A, Tseng WJ, Mishra MK, Shore EM, Khurana TS. Loro E, et al. Among authors: chandra a. Bone. 2017 Oct;103:20-30. doi: 10.1016/j.bone.2017.06.003. Epub 2017 Jun 6. Bone. 2017. PMID: 28602725 Free PMC article.

5

Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis.

Chandra A, Wang L, Young T, Zhong L, Tseng WJ, Levine MA, Cengel K, Liu XS, Zhang Y, Pignolo RJ, Qin L. Chandra A, et al. FASEB J. 2018 Jan;32(1):52-62. doi: 10.1096/fj.201700375R. Epub 2017 Aug 31. FASEB J. 2018. PMID: 28860152 Free PMC article.

Meanwhile, it also inhibited bone marrow adiposity. Taken together, we demonstrate a novel role of proteasome inhibitors in treating radiation-induced osteoporosis.-Chandra, A., Wang, L., Young, T., Zhong, L., Tseng, W.-J., Levine, M. A., Cengel, K., L …

Meanwhile, it also inhibited bone marrow adiposity. Taken together, we demonstrate a novel role of proteasome inhibitors in treating …

6

Potential role of senescence in radiation-induced damage of the aged skeleton.

Chandra A, Park SS, Pignolo RJ. Chandra A, et al. Bone. 2019 Mar;120:423-431. doi: 10.1016/j.bone.2018.12.006. Epub 2018 Dec 10. Bone. 2019. PMID: 30543989 Review.

7

Targeting Cell Senescence for the Treatment of Age-Related Bone Loss.

Pignolo RJ, Samsonraj RM, Law SF, Wang H, Chandra A. Pignolo RJ, et al. Among authors: chandra a. Curr Osteoporos Rep. 2019 Apr;17(2):70-85. doi: 10.1007/s11914-019-00504-2. Curr Osteoporos Rep. 2019. PMID: 30806947 Review.

8

Bone Aging, Cellular Senescence, and Osteoporosis.

Pignolo RJ, Law SF, Chandra A. Pignolo RJ, et al. Among authors: chandra a. JBMR Plus. 2021 Apr 2;5(4):e10488. doi: 10.1002/jbm4.10488. eCollection 2021 Apr. JBMR Plus. 2021. PMID: 33869998 Free PMC article. Review.

9

Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence.

Chandra A, Lagnado AB, Farr JN, Schleusner M, Monroe DG, Saul D, Passos JF, Khosla S, Pignolo RJ. Chandra A, et al. J Bone Miner Res. 2022 May;37(5):997-1011. doi: 10.1002/jbmr.4537. Epub 2022 Mar 29. J Bone Miner Res. 2022. PMID: 35247283 Free PMC article.

10

Targeted clearance of p21- but not p16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity.

Chandra A, Lagnado AB, Farr JN, Doolittle M, Tchkonia T, Kirkland JL, LeBrasseur NK, Robbins PD, Niedernhofer LJ, Ikeno Y, Passos JF, Monroe DG, Pignolo RJ, Khosla S. Chandra A, et al. Aging Cell. 2022 May;21(5):e13602. doi: 10.1111/acel.13602. Epub 2022 Apr 1. Aging Cell. 2022. PMID: 35363946 Free PMC article.

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