Al-Moghrabi N - Search Results

1

Curcumin induces re‑expression of BRCA1 and suppression of γ synuclein by modulating DNA promoter methylation in breast cancer cell lines.

Al-Yousef N, Shinwari Z, Al-Shahrani B, Al-Showimi M, Al-Moghrabi N. Al-Yousef N, et al. Among authors: al moghrabi n. Oncol Rep. 2020 Mar;43(3):827-838. doi: 10.3892/or.2020.7473. Epub 2020 Jan 20. Oncol Rep. 2020. PMID: 32020216 Free PMC article.

2

Methylation-related mutations in the BRCA1 promoter in peripheral blood cells from cancer-free women.

Al-Moghrabi N, Al-Qasem AJ, Aboussekhra A. Al-Moghrabi N, et al. Int J Oncol. 2011 Jul;39(1):129-35. doi: 10.3892/ijo.2011.1021. Epub 2011 Apr 29. Int J Oncol. 2011. PMID: 21537840

3

The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females.

Al-Moghrabi N, Nofel A, Al-Yousef N, Madkhali S, Bin Amer SM, Alaiya A, Shinwari Z, Al-Tweigeri T, Karakas B, Tulbah A, Aboussekhra A. Al-Moghrabi N, et al. BMC Cancer. 2014 Nov 17;14:830. doi: 10.1186/1471-2407-14-830. BMC Cancer. 2014. PMID: 25403427 Free PMC article.

4

High prevalence of deleterious BRCA1 and BRCA2 germline mutations in arab breast and ovarian cancer patients.

Alhuqail AJ, Alzahrani A, Almubarak H, Al-Qadheeb S, Alghofaili L, Almoghrabi N, Alhussaini H, Park BH, Colak D, Karakas B. Alhuqail AJ, et al. Breast Cancer Res Treat. 2018 Apr;168(3):695-702. doi: 10.1007/s10549-017-4635-4. Epub 2018 Jan 2. Breast Cancer Res Treat. 2018. PMID: 29297111

5

Methylation of BRCA1 and MGMT genes in white blood cells are transmitted from mothers to daughters.

Al-Moghrabi N, Al-Showimi M, Al-Yousef N, Al-Shahrani B, Karakas B, Alghofaili L, Almubarak H, Madkhali S, Al Humaidan H. Al-Moghrabi N, et al. Clin Epigenetics. 2018 Jul 26;10(1):99. doi: 10.1186/s13148-018-0529-5. Clin Epigenetics. 2018. PMID: 30049288 Free PMC article.

6

BRCA1 promoter methylation in peripheral blood cells and predisposition to breast cancer.

Al-Moghrabi NM. Al-Moghrabi NM. J Taibah Univ Med Sci. 2017 Feb 22;12(3):189-193. doi: 10.1016/j.jtumed.2017.01.004. eCollection 2017 Jun. J Taibah Univ Med Sci. 2017. PMID: 31435238 Free PMC article. Review.

7

Eugenol modulates genomic methylation and inactivates breast cancer-associated fibroblasts through E2F1-dependent downregulation of DNMT1/DNMT3A.

Al-Kharashi LA, Bakheet T, AlHarbi WA, Al-Moghrabi N, Aboussekhra A. Al-Kharashi LA, et al. Among authors: al moghrabi n. Mol Carcinog. 2021 Nov;60(11):784-795. doi: 10.1002/mc.23344. Epub 2021 Sep 2. Mol Carcinog. 2021. PMID: 34473867

8

MicroRNA-126 expression in the peripheral white blood cells of patients with breast and ovarian cancer is a potential biomarker for the early prediction of cancer risk in the carriers of methylated BRCA1.

Al-Showimi M, Al-Yousef N, Alharbi W, Alkhezayem S, Almalik O, Alhusaini H, Alghamdi A, Al-Moghrabi N. Al-Showimi M, et al. Among authors: al moghrabi n. Oncol Lett. 2022 Jun 22;24(2):276. doi: 10.3892/ol.2022.13396. eCollection 2022 Aug. Oncol Lett. 2022. PMID: 35782895 Free PMC article.

9

MicroRNA-155-5p, Reduced by Curcumin-Re-Expressed Hypermethylated BRCA1, Is a Molecular Biomarker for Cancer Risk in BRCA1-methylation Carriers.

Al-Moghrabi N, Al-Showimi M, Al-Yousef N, AlOtai L. Al-Moghrabi N, et al. Int J Mol Sci. 2023 May 19;24(10):9021. doi: 10.3390/ijms24109021. Int J Mol Sci. 2023. PMID: 37240365 Free PMC article.

10

Constitutional BRCA1 and MGMT Methylation Are Significant Risk Factors for Triple-Negative Breast Cancer and High-Grade Serous Ovarian Cancer in Saudi Women.

Al-Moghrabi N, Al-Showimi M, Alqahtani A, Almalik O, Alhusaini H, Almalki G, Saad A, Alsunayi E. Al-Moghrabi N, et al. Int J Mol Sci. 2024 Mar 7;25(6):3108. doi: 10.3390/ijms25063108. Int J Mol Sci. 2024. PMID: 38542081 Free PMC article.

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