Cai Z - Search Results

1

The Skp2 Pathway: A Critical Target for Cancer Therapy.

Cai Z, Moten A, Peng D, Hsu CC, Pan BS, Manne R, Li HY, Lin HK. Cai Z, et al. Semin Cancer Biol. 2020 Dec;67(Pt 2):16-33. doi: 10.1016/j.semcancer.2020.01.013. Epub 2020 Feb 1. Semin Cancer Biol. 2020. PMID: 32014608 Free PMC article. Review.

2

AMPK signaling and its targeting in cancer progression and treatment.

Hsu CC, Peng D, Cai Z, Lin HK. Hsu CC, et al. Among authors: cai z. Semin Cancer Biol. 2022 Oct;85:52-68. doi: 10.1016/j.semcancer.2021.04.006. Epub 2021 Apr 18. Semin Cancer Biol. 2022. PMID: 33862221 Free PMC article. Review.

3

Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress.

Lee SW, Li CF, Jin G, Cai Z, Han F, Chan CH, Yang WL, Li BK, Rezaeian AH, Li HY, Huang HY, Lin HK. Lee SW, et al. Among authors: cai z. Mol Cell. 2015 Mar 19;57(6):1022-1033. doi: 10.1016/j.molcel.2015.01.015. Epub 2015 Feb 26. Mol Cell. 2015. PMID: 25728766 Free PMC article.

4

Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis.

Cai Z, Li CF, Han F, Liu C, Zhang A, Hsu CC, Peng D, Zhang X, Jin G, Rezaeian AH, Wang G, Zhang W, Pan BS, Wang CY, Wang YH, Wu SY, Yang SC, Hsu FC, D'Agostino RB Jr, Furdui CM, Kucera GL, Parks JS, Chilton FH, Huang CY, Tsai FJ, Pasche B, Watabe K, Lin HK. Cai Z, et al. Mol Cell. 2020 Oct 15;80(2):263-278.e7. doi: 10.1016/j.molcel.2020.09.018. Epub 2020 Oct 5. Mol Cell. 2020. PMID: 33022274 Free PMC article.

5

Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression.

Chan CH, Morrow JK, Li CF, Gao Y, Jin G, Moten A, Stagg LJ, Ladbury JE, Cai Z, Xu D, Logothetis CJ, Hung MC, Zhang S, Lin HK. Chan CH, et al. Among authors: cai z. Cell. 2013 Aug 1;154(3):556-68. doi: 10.1016/j.cell.2013.06.048. Cell. 2013. PMID: 23911321 Free PMC article.

6

The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance.

Han F, Li CF, Cai Z, Zhang X, Jin G, Zhang WN, Xu C, Wang CY, Morrow J, Zhang S, Xu D, Wang G, Lin HK. Han F, et al. Among authors: cai z. Nat Commun. 2018 Nov 9;9(1):4728. doi: 10.1038/s41467-018-07188-9. Nat Commun. 2018. PMID: 30413706 Free PMC article.

7

SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis.

Wang G, Long J, Gao Y, Zhang W, Han F, Xu C, Sun L, Yang SC, Lan J, Hou Z, Cai Z, Jin G, Hsu CC, Wang YH, Hu J, Chen TY, Li H, Lee MG, Lin HK. Wang G, et al. Among authors: cai z. Nat Cell Biol. 2019 Feb;21(2):214-225. doi: 10.1038/s41556-018-0266-1. Epub 2019 Jan 28. Nat Cell Biol. 2019. PMID: 30692626 Free PMC article.

8

AMPK maintains TCA cycle through sequential phosphorylation of PDHA to promote tumor metastasis.

Cai Z, Peng D, Lin HK. Cai Z, et al. Cell Stress. 2020 Nov 25;4(12):273-277. doi: 10.15698/cst2020.12.238. Cell Stress. 2020. PMID: 33336150 Free PMC article.

9

Author Correction: SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis.

Wang G, Long J, Gao Y, Zhang W, Han F, Xu C, Sun L, Yang SC, Lan J, Hou Z, Cai Z, Jin G, Hsu CC, Wang YH, Hu J, Chen TY, Li H, Lee MG, Lin HK. Wang G, et al. Among authors: cai z. Nat Cell Biol. 2021 Jun;23(6):676. doi: 10.1038/s41556-021-00686-x. Nat Cell Biol. 2021. PMID: 33927372

10

Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK.

Hsu CC, Zhang X, Wang G, Zhang W, Cai Z, Pan BS, Gu H, Xu C, Jin G, Xu X, Manne RK, Jin Y, Yan W, Shao J, Chen T, Lin E, Ketkar A, Eoff R, Xu ZG, Chen ZZ, Li HY, Lin HK. Hsu CC, et al. Among authors: cai z. Mol Cell. 2021 Sep 16;81(18):3803-3819.e7. doi: 10.1016/j.molcel.2021.08.025. Mol Cell. 2021. PMID: 34547240 Free PMC article.

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