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Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography.
Amaral PA, Autheman D, de Melo GD, Gouault N, Cupif JF, Goyard S, Dutra P, Coatnoan N, Cosson A, Monet D, Saul F, Haouz A, Uriac P, Blondel A, Minoprio P. Amaral PA, et al. Among authors: de melo gd. PLoS Negl Trop Dis. 2018 Oct 29;12(10):e0006853. doi: 10.1371/journal.pntd.0006853. eCollection 2018 Oct. PLoS Negl Trop Dis. 2018. PMID: 30372428 Free PMC article.
A combination of two human monoclonal antibodies cures symptomatic rabies.
de Melo GD, Sonthonnax F, Lepousez G, Jouvion G, Minola A, Zatta F, Larrous F, Kergoat L, Mazo C, Moigneu C, Aiello R, Salomoni A, Brisebard E, De Benedictis P, Corti D, Bourhy H. de Melo GD, et al. Among authors: de benedictis p. EMBO Mol Med. 2020 Nov 6;12(11):e12628. doi: 10.15252/emmm.202012628. Epub 2020 Sep 18. EMBO Mol Med. 2020. PMID: 32945125 Free PMC article.
[New aspects of rabies control].
Bourhy H, de Melo GD, Tarantola A. Bourhy H, et al. Among authors: de melo gd. Bull Acad Natl Med. 2020 Dec;204(9):1000-1009. doi: 10.1016/j.banm.2020.09.036. Epub 2020 Sep 18. Bull Acad Natl Med. 2020. PMID: 32981935 Free PMC article. Review. French.
COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters.
de Melo GD, Lazarini F, Levallois S, Hautefort C, Michel V, Larrous F, Verillaud B, Aparicio C, Wagner S, Gheusi G, Kergoat L, Kornobis E, Donati F, Cokelaer T, Hervochon R, Madec Y, Roze E, Salmon D, Bourhy H, Lecuit M, Lledo PM. de Melo GD, et al. Sci Transl Med. 2021 Jun 2;13(596):eabf8396. doi: 10.1126/scitranslmed.abf8396. Epub 2021 May 3. Sci Transl Med. 2021. PMID: 33941622 Free PMC article.
SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance.
Robinot R, Hubert M, de Melo GD, Lazarini F, Bruel T, Smith N, Levallois S, Larrous F, Fernandes J, Gellenoncourt S, Rigaud S, Gorgette O, Thouvenot C, Trébeau C, Mallet A, Duménil G, Gobaa S, Etournay R, Lledo PM, Lecuit M, Bourhy H, Duffy D, Michel V, Schwartz O, Chakrabarti LA. Robinot R, et al. Among authors: de melo gd. Nat Commun. 2021 Jul 16;12(1):4354. doi: 10.1038/s41467-021-24521-x. Nat Commun. 2021. PMID: 34272374 Free PMC article.
A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters.
Frantz PN, Barinov A, Ruffié C, Combredet C, Najburg V, de Melo GD, Larrous F, Kergoat L, Teeravechyan S, Jongkaewwattana A, Billon-Denis E, Tournier JN, Prot M, Levillayer L, Conquet L, Montagutelli X, Tichit M, Hardy D, Fernandes P, Strick-Marchand H, Di Santo J, Simon-Lorière E, Bourhy H, Tangy F. Frantz PN, et al. Among authors: de melo gd. Nat Commun. 2021 Nov 1;12(1):6277. doi: 10.1038/s41467-021-26506-2. Nat Commun. 2021. PMID: 34725327 Free PMC article.
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Park YJ, Pinto D, Walls AC, Liu Z, Marco A, Benigni F, Zatta F, Silacci-Fregni C, Bassi J, Sprouse KR, Addetia A, Bowen JE, Stewart C, Giurdanella M, Saliba C, Guarino B, Schmid MA, Franko N, Logue J, Dang HV, Hauser K, Iulio JD, Rivera W, Schnell G, Rajesh A, Zhou J, Farhat N, Kaiser H, Montiel-Ruiz M, Noack J, Lempp FA, Janer J, Abdelnabi R, Maes P, Ferrari P, Ceschi A, Giannini O, de Melo GD, Kergoat L, Bourhy H, Neyts J, Soriaga L, Purcell LA, Snell G, Whelan SPJ, Lanzavecchia A, Virgin HW, Piccoli L, Chu H, Pizzuto MS, Corti D, Veesler D. Park YJ, et al. Among authors: de melo gd. bioRxiv [Preprint]. 2022 Aug 22:2022.05.08.491108. doi: 10.1101/2022.05.08.491108. bioRxiv. 2022. Update in: Science. 2022 Nov 11;378(6620):619-627. doi: 10.1126/science.adc9127 PMID: 35677069 Free PMC article. Updated. Preprint.
36 results