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Allosteric targeting resolves limitations of earlier LFA-1 directed modalities.
Mancuso RV, Schneider G, Hürzeler M, Gut M, Zurflüh J, Breitenstein W, Bouitbir J, Reisen F, Atz K, Ehrhardt C, Duthaler U, Gygax D, Schmidt AG, Krähenbühl S, Weitz-Schmidt G. Mancuso RV, et al. Among authors: schmidt ag. Biochem Pharmacol. 2023 May;211:115504. doi: 10.1016/j.bcp.2023.115504. Epub 2023 Mar 14. Biochem Pharmacol. 2023. PMID: 36921634
A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice.
Case JB, Sanapala S, Dillen C, Rhodes V, Zmasek C, Chicz TM, Switzer CE, Scheaffer SM, Georgiev G, Jacob-Dolan C, Hauser BM, Dos Anjos DCC, Adams LJ, Soudani N, Liang CY, Ying B, McNamara RP, Scheuermann RH, Boon ACM, Fremont DH, Whelan SPJ, Schmidt AG, Sette A, Grifoni A, Frieman MB, Diamond MS. Case JB, et al. Among authors: schmidt ag. Cell Host Microbe. 2024 Dec 11;32(12):2131-2147.e8. doi: 10.1016/j.chom.2024.10.016. Epub 2024 Nov 18. Cell Host Microbe. 2024. PMID: 39561781 Free article.
Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Ray R, Nait Mohamed FA, Maurer DP, Huang J, Alpay BA, Ronsard L, Xie Z, Han J, Fernandez-Quintero M, Phan QA, Ursin RL, Vu M, Kirsch KH, Prum T, Rosado VC, Bracamonte-Moreno T, Okonkwo V, Bals J, McCarthy C, Nair U, Kanekiyo M, Ward AB, Schmidt AG, Batista FD, Lingwood D. Ray R, et al. Among authors: schmidt ag. Immunity. 2024 May 14;57(5):1141-1159.e11. doi: 10.1016/j.immuni.2024.03.022. Epub 2024 Apr 25. Immunity. 2024. PMID: 38670113 Free PMC article.
B cell somatic hypermutation following COVID-19 vaccination with Ad26.COV2.S.
Jacob-Dolan C, Lifton M, Powers OC, Miller J, Hachmann NP, Vu M, Surve N, Mazurek CR, Fisher JL, Rodrigues S, Patio RC, Anand T, Le Gars M, Sadoff J, Schmidt AG, Barouch DH. Jacob-Dolan C, et al. Among authors: schmidt ag. iScience. 2024 Apr 9;27(5):109716. doi: 10.1016/j.isci.2024.109716. eCollection 2024 May 17. iScience. 2024. PMID: 38655202 Free PMC article.
163 results