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The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites.
Yoo E, Schulze CJ, Stokes BH, Onguka O, Yeo T, Mok S, Gnädig NF, Zhou Y, Kurita K, Foe IT, Terrell SM, Boucher MJ, Cieplak P, Kumpornsin K, Lee MCS, Linington RG, Long JZ, Uhlemann AC, Weerapana E, Fidock DA, Bogyo M. Yoo E, et al. Among authors: bogyo m. Cell Chem Biol. 2020 Feb 20;27(2):143-157.e5. doi: 10.1016/j.chembiol.2020.01.001. Epub 2020 Jan 23. Cell Chem Biol. 2020. PMID: 31978322 Free PMC article.
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion.
Hall CI, Reese ML, Weerapana E, Child MA, Bowyer PW, Albrow VE, Haraldsen JD, Phillips MR, Sandoval ED, Ward GE, Cravatt BF, Boothroyd JC, Bogyo M. Hall CI, et al. Among authors: bogyo m. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10568-73. doi: 10.1073/pnas.1105622108. Epub 2011 Jun 13. Proc Natl Acad Sci U S A. 2011. PMID: 21670272 Free PMC article.
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion.
Child MA, Hall CI, Beck JR, Ofori LO, Albrow VE, Garland M, Bowyer PW, Bradley PJ, Powers JC, Boothroyd JC, Weerapana E, Bogyo M. Child MA, et al. Among authors: bogyo m. Nat Chem Biol. 2013 Oct;9(10):651-6. doi: 10.1038/nchembio.1315. Epub 2013 Aug 11. Nat Chem Biol. 2013. PMID: 23934245 Free PMC article.
Global Analysis of Palmitoylated Proteins in Toxoplasma gondii.
Foe IT, Child MA, Majmudar JD, Krishnamurthy S, van der Linden WA, Ward GE, Martin BR, Bogyo M. Foe IT, et al. Among authors: bogyo m. Cell Host Microbe. 2015 Oct 14;18(4):501-11. doi: 10.1016/j.chom.2015.09.006. Cell Host Microbe. 2015. PMID: 26468752 Free PMC article.
Cysteine Cathepsin Inhibitors as Anti-Ebola Agents.
van der Linden WA, Schulze CJ, Herbert AS, Krause TB, Wirchnianski AA, Dye JM, Chandran K, Bogyo M. van der Linden WA, et al. Among authors: bogyo m. ACS Infect Dis. 2016 Mar 11;2(3):173-179. doi: 10.1021/acsinfecdis.5b00130. Epub 2016 Jan 20. ACS Infect Dis. 2016. PMID: 27347558 Free PMC article.
An in vivo multiplexed small-molecule screening platform.
Grüner BM, Schulze CJ, Yang D, Ogasawara D, Dix MM, Rogers ZN, Chuang CH, McFarland CD, Chiou SH, Brown JM, Cravatt BF, Bogyo M, Winslow MM. Grüner BM, et al. Among authors: bogyo m. Nat Methods. 2016 Oct;13(10):883-889. doi: 10.1038/nmeth.3992. Epub 2016 Sep 12. Nat Methods. 2016. PMID: 27617390 Free PMC article.
316 results