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Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases.
Hayashi K, Teramoto R, Nomura A, Asano Y, Beerens M, Kurata Y, Kobayashi I, Fujino N, Furusho H, Sakata K, Onoue K, Chiang DY, Kiviniemi TO, Buys E, Sips P, Burch ML, Zhao Y, Kelly AE, Namura M, Kita Y, Tsuchiya T, Kaku B, Oe K, Takeda Y, Konno T, Inoue M, Fujita T, Kato T, Funada A, Tada H, Hodatsu A, Nakanishi C, Sakamoto Y, Tsuda T, Nagata Y, Tanaka Y, Okada H, Usuda K, Cui S, Saito Y, MacRae CA, Takashima S, Yamagishi M, Kawashiri MA, Takamura M. Hayashi K, et al. Among authors: macrae ca. Cardiovasc Res. 2020 Nov 1;116(13):2116-2130. doi: 10.1093/cvr/cvaa010. Cardiovasc Res. 2020. PMID: 31977013 Free PMC article.
Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning.
Sips PY, Shi X, Musso G, Nath AK, Zhao Y, Nielson J, Morningstar J, Kelly AE, Mikell B, Buys E, Bebarta V, Rutter J, Davisson VJ, Mahon S, Brenner M, Boss GR, Peterson RT, Gerszten RE, MacRae CA. Sips PY, et al. Among authors: macrae ca. PLoS One. 2018 Jun 7;13(6):e0193889. doi: 10.1371/journal.pone.0193889. eCollection 2018. PLoS One. 2018. PMID: 29879736 Free PMC article.
Zebrafish model of amyloid light chain cardiotoxicity: regeneration versus degeneration.
Mishra S, Joshi S, Ward JE, Buys EP, Mishra D, Mishra D, Morgado I, Fisch S, Lavatelli F, Merlini G, Dorbala S, MacRae CA, Liao R. Mishra S, et al. Among authors: macrae ca. Am J Physiol Heart Circ Physiol. 2019 May 1;316(5):H1158-H1166. doi: 10.1152/ajpheart.00788.2018. Epub 2019 Mar 15. Am J Physiol Heart Circ Physiol. 2019. PMID: 30875258 Free PMC article.
LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor) Regulates Cardiac L-Type Calcium Channels by Modulating NEDD (Neural Precursor Cell Expressed Developmentally Downregulated Protein) 4-1 Ubiquitin Ligase.
Moshal KS, Roder K, Kabakov AY, Werdich AA, Chiang DY, Turan NN, Xie A, Kim TY, Cooper LL, Lu Y, Zhong M, Li W, Terentyev D, Choi BR, Karma A, MacRae CA, Koren G. Moshal KS, et al. Among authors: macrae ca. Circ Genom Precis Med. 2019 Sep;12(9):407-420. doi: 10.1161/CIRCGEN.119.002641. Epub 2019 Aug 28. Circ Genom Precis Med. 2019. PMID: 31462068 Free PMC article.
Metastable Atrial State Underlies the Primary Genetic Substrate for MYL4 Mutation-Associated Atrial Fibrillation.
Ghazizadeh Z, Kiviniemi T, Olafsson S, Plotnick D, Beerens ME, Zhang K, Gillon L, Steinbaugh MJ, Barrera V, Sui SH, Werdich AA, Kapur S, Eranti A, Gunn J, Jalkanen J, Airaksinen J, Kleber AG, Hollmén M, MacRae CA. Ghazizadeh Z, et al. Among authors: macrae ca. Circulation. 2020 Jan 28;141(4):301-312. doi: 10.1161/CIRCULATIONAHA.119.044268. Epub 2019 Nov 16. Circulation. 2020. PMID: 31735076 Free article.
Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs.
Marchal GA, Jouni M, Chiang DY, Pérez-Hernández M, Podliesna S, Yu N, Casini S, Potet F, Veerman CC, Klerk M, Lodder EM, Mengarelli I, Guan K, Vanoye CG, Rothenberg E, Charpentier F, Redon R, George AL Jr, Verkerk AO, Bezzina CR, MacRae CA, Burridge PW, Delmar M, Galjart N, Portero V, Remme CA. Marchal GA, et al. Among authors: macrae ca. Circ Res. 2021 Jul 23;129(3):349-365. doi: 10.1161/CIRCRESAHA.120.318643. Epub 2021 Jun 7. Circ Res. 2021. PMID: 34092082 Free PMC article.
MIC-Drop: A platform for large-scale in vivo CRISPR screens.
Parvez S, Herdman C, Beerens M, Chakraborti K, Harmer ZP, Yeh JJ, MacRae CA, Yost HJ, Peterson RT. Parvez S, et al. Among authors: macrae ca. Science. 2021 Sep 3;373(6559):1146-1151. doi: 10.1126/science.abi8870. Epub 2021 Aug 19. Science. 2021. PMID: 34413171 Free PMC article.
376 results