Zhang L - Search Results

1

Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.

Zhang L, Davies JS, Serna C, Yu Z, Restifo NP, Rosenberg SA, Morgan RA, Hinrichs CS. Zhang L, et al. J Immunother Cancer. 2020 Jan;8(1):e000210. doi: 10.1136/jitc-2019-000210. J Immunother Cancer. 2020. PMID: 31959727 Free PMC article.

2

Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts.

Kerkar SP, Muranski P, Kaiser A, Boni A, Sanchez-Perez L, Yu Z, Palmer DC, Reger RN, Borman ZA, Zhang L, Morgan RA, Gattinoni L, Rosenberg SA, Trinchieri G, Restifo NP. Kerkar SP, et al. Among authors: zhang l. Cancer Res. 2010 Sep 1;70(17):6725-34. doi: 10.1158/0008-5472.CAN-10-0735. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647327 Free PMC article.

3

Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment.

Zhang L, Kerkar SP, Yu Z, Zheng Z, Yang S, Restifo NP, Rosenberg SA, Morgan RA. Zhang L, et al. Mol Ther. 2011 Apr;19(4):751-9. doi: 10.1038/mt.2010.313. Epub 2011 Feb 1. Mol Ther. 2011. PMID: 21285960 Free PMC article.

4

The position of the AUG start codon in MFG-based γ-retroviral vectors has a dramatic effect on translation-dependent protein expression.

Frankel TL, Zhang L, Burns WR, Zheng Z, Morgan RA. Frankel TL, et al. Among authors: zhang l. J Gene Med. 2011 Sep;13(9):478-86. doi: 10.1002/jgm.1599. J Gene Med. 2011. PMID: 21796743

5

Genetic engineering with T cell receptors.

Zhang L, Morgan RA. Zhang L, et al. Adv Drug Deliv Rev. 2012 Jun 1;64(8):756-62. doi: 10.1016/j.addr.2011.11.009. Epub 2011 Dec 9. Adv Drug Deliv Rev. 2012. PMID: 22178904 Free PMC article. Review.

6

Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice.

Chinnasamy D, Yu Z, Kerkar SP, Zhang L, Morgan RA, Restifo NP, Rosenberg SA. Chinnasamy D, et al. Among authors: zhang l. Clin Cancer Res. 2012 Mar 15;18(6):1672-83. doi: 10.1158/1078-0432.CCR-11-3050. Epub 2012 Jan 30. Clin Cancer Res. 2012. PMID: 22291136 Free PMC article.

7

Evaluation of γ-retroviral vectors that mediate the inducible expression of IL-12 for clinical application.

Zhang L, Feldman SA, Zheng Z, Chinnasamy N, Xu H, Nahvi AV, Dudley ME, Rosenberg SA, Morgan RA. Zhang L, et al. J Immunother. 2012 Jun;35(5):430-9. doi: 10.1097/CJI.0b013e31825898e8. J Immunother. 2012. PMID: 22576348 Free PMC article.

8

Modulating the differentiation status of ex vivo-cultured anti-tumor T cells using cytokine cocktails.

Yang S, Ji Y, Gattinoni L, Zhang L, Yu Z, Restifo NP, Rosenberg SA, Morgan RA. Yang S, et al. Among authors: zhang l. Cancer Immunol Immunother. 2013 Apr;62(4):727-36. doi: 10.1007/s00262-012-1378-2. Epub 2012 Dec 4. Cancer Immunol Immunother. 2013. PMID: 23207483 Free PMC article.

9

Collapse of the tumor stroma is triggered by IL-12 induction of Fas.

Kerkar SP, Leonardi AJ, van Panhuys N, Zhang L, Yu Z, Crompton JG, Pan JH, Palmer DC, Morgan RA, Rosenberg SA, Restifo NP. Kerkar SP, et al. Among authors: zhang l. Mol Ther. 2013 Jul;21(7):1369-77. doi: 10.1038/mt.2013.58. Epub 2013 Apr 9. Mol Ther. 2013. PMID: 23568260 Free PMC article.

10

Gamma-retroviral vector design for the co-expression of artificial microRNAs and therapeutic proteins.

Park TS, Abate-Daga D, Zhang L, Zheng Z, Morgan RA. Park TS, et al. Among authors: zhang l. Nucleic Acid Ther. 2014 Oct;24(5):356-63. doi: 10.1089/nat.2014.0486. Epub 2014 Jul 14. Nucleic Acid Ther. 2014. PMID: 25019196 Free PMC article.

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