Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes.
Okamato Y, Ghosh T, Okamoto T, Schuyler RP, Seifert J, Charry LL, Visser A, Feser M, Fleischer C, Pedrick C, August J, Moss L, Bemis EA, Norris JM, Kuhn KA, Demoruelle MK, Deane KD, Ghosh D, Holers VM, Hsieh EWY.
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J Autoimmun. 2021 Feb;117:102581. doi: 10.1016/j.jaut.2020.102581. Epub 2020 Dec 9.
J Autoimmun. 2021.
PMID: 33310262
Free PMC article.